La familia del pintor (The painter's family) 1622 (close up) by Jacob Jordaens
Jacob Jordaens
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Source: Firestein, Gary S. (15 May 2003). "Evolving concepts of rheumatoid arthritis" Nature. 423 (6937):
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Conclusions. 1 . It has been possible to relieve patents of all or practically all, symptoms of diffuse arthritis by a large curtailment of carbohydrates.
THE METABOLISM AND TREATMENT OF RHEUMATOID ARTHRITIS. FOURTH PAPER by RALPH PENBERTON The American Journal of the Medical Sciences Publication date 1917-05 https://archive.org/details/paper-doi-10_1097_00000441-191705000-00005 video: How do carbohydrates impact your health? - Richard J. Wood https://www.youtube.com/watch?v=wxzc_2c6GMg |
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How I put my diagnosed, juvenile rheumatoid arthritis active in 37 joints into remission with an extreme elimination diet of only eating meat. https://www.youtube.com/watch?v=0ka9WBEijhk Mikhaila Peterson |
Rheumatoid Arthritis: Prevention and Treatment with a Plant-Based Diet
Rheumatoid arthritis has no cure, so long term treatment is indicated. An individual's dietary choices greatly influence the progression of chronic autoimmune rheumatic diseases. This review shows that the plant-based diet has good scientific evidence of safety and efficacy for both prevention and treatment of rheumatoid arthritis.
Source:
Rheumatoid Arthritis: Prevention and Treatment with a Plant-Based Diet: https://pbdmedicine.org/rheumatoid-arthritis-plant-based-diets-can-help/
Rheumatoid arthritis has no cure, so long term treatment is indicated. An individual's dietary choices greatly influence the progression of chronic autoimmune rheumatic diseases. This review shows that the plant-based diet has good scientific evidence of safety and efficacy for both prevention and treatment of rheumatoid arthritis.
Source:
Rheumatoid Arthritis: Prevention and Treatment with a Plant-Based Diet: https://pbdmedicine.org/rheumatoid-arthritis-plant-based-diets-can-help/
Mineral for strengthening your bones
www.youtube.com/watch?v=1T_L9qBcePk WONDER WHY THE PALMS OF YOUR HANDS ARE SO RED. . Dr. Eric Berg October 23 2021 9 Signs of Toxin Build-up in the Liver Today we’re going to talk about the nine things your skin can tell you about your liver. https://www.facebook.com/drericberg/videos/1205403849944126 ALT: Seven Remedies for an Inflamed Liver https://www.facebook.com/watch/?v=1205403849944126 |
Osteoporosis and flavonoids
Osteoporosis is a disease in which bones become fragile and easily break. The mineral density of bones is decreased which makes them fragile. Typically fractures are present in hip and spine bones, in addition to wrist bones. Women are more likely than men to develop osteoporosis because of estrogen deficiency after menopause. Isoflavones in soy have a weak estrogen-like activity and thus they are interesting as they may be potential in osteoporosis prevention. In some studies, intervention as well as epidemiological studies, a protective effect of soy against osteoporosis has been detected. However, as soy also contains calcium, it may partly explain the effect. Among other types of flavonoids the consumption of tea (tea contains catechins) has been associated with higher bone mineral density.
Osteoporosis is a disease in which bones become fragile and easily break. The mineral density of bones is decreased which makes them fragile. Typically fractures are present in hip and spine bones, in addition to wrist bones. Women are more likely than men to develop osteoporosis because of estrogen deficiency after menopause. Isoflavones in soy have a weak estrogen-like activity and thus they are interesting as they may be potential in osteoporosis prevention. In some studies, intervention as well as epidemiological studies, a protective effect of soy against osteoporosis has been detected. However, as soy also contains calcium, it may partly explain the effect. Among other types of flavonoids the consumption of tea (tea contains catechins) has been associated with higher bone mineral density.
The phytoconstituents like those listed below, and others (steroid and fatty acid) tend to inhibit the osteoclastogenesis. https://onlinelibrary.wiley.com/doi/pdf/10.1111/jphp.13326
Osteoclastogenesis is the formation of bone-resorbing cells, called osteoclasts, from precursor cells of myeloid origin. A physical contact of precursor cells with osteoblasts or other specific mesenchymal cells, such as stromal or synovial cells, is essential for osteoclastogenesis.
flavonoids
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glycosides
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lignans
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coumarins
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alkaloids
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polyphenols
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limonoids
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quinones
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terpenoids
1. sesquiterpenoids 2. diterpenoids triterpenoids |
Flavonoids
What are the different classes of Flavonoids?
1. Flavonols Good sources of flavonols in the diet are onion, kale, broccoli, lettuce, tomato, apple, grape, berries, tea, red wine. The greener the leaf is, the more it contains flavonols. There are large differences between different varieties in their flavonoid content. Among cruciferous crops the highest flavonoid content has been found in curly cale. The major dietary flavonols are quercetin, kaempferol, myricetin and isorhamnetin. 2. Flavones Good sources of flavones in the diet are celery and parsley. The major dietary flavones are luteolin and apigenin. 3. Isoflavonoids Isoflavones, which have potent antioxidant properties comparable to that of vitamin E, can reduce the long-term risk of cancer by preventing free radical damage to DNA. The major dietary sources are soy beans and soy products. The isoflavonoid content of some soy products is presented. Different types of soy cheeses, soy flour, Soy bean, Tofu 4. Flavonones Good sources of flavanones are citrus fruit Orange, Grapefruit, Lemon The major dietary flavanones c are hesperetin, naringenin and eriodictyol. The major dietary isoflavones are daidzein, genistein and glycitein. 5. Anthocyanosides Tend to be red, violet or blue Anthocyanosides or anthocyanins are specific chemical elements in plants that control pigmentation. These chemicals are known as super-antioxidants. They are highly prized as health boosting substances because of their antioxidant properties. Antioxidants help to preserve the body and fight off viruses, infections, and inflammations. Anthocyanins are the violet, blue and purple colourants, mainly in fruits, berries and flowers. Violet antocyanins colour black currant, red cabbage, plum and the blue potato ‘Blue Congo’. Red antocyanins are present in red berries like lingonberry, cranberry and red currant. The major dietary anthocyanins are cyanidin, delphinidin, malvidin, pelargonidin, peonidin and petunidin. 6. Chalcones Chalcone derivatives have been widely used for the treatment of viral disorders, cardiovascular diseases, stomach cancer, food additives, and cosmetic formulation ingredients. They are natural compounds present in edible plants. Chalcones are a class of natural compounds that belong to flavonoids and are present in many edible plants such as fruits (tomatoes, apples, citrus), nuts, and vegetables (potatoes, shallots, bean sprouts) with anti-inflammatory, antibacterial, antiviral, anticancer, and antioxidant properties. https://www.researchgate.net/publication/292048430_Naturally_occurring_chalcones_and_their_biological_activities#:~:text=Chalcones%20are%20a%20class%20of,%2C%20anticancer%2C%20and%20antioxidant%20properties. |
Glycosides
Lignans
Polyphenols are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases such as cancer and cardiovascular diseases is emerging.
Source: Polyphenols: food sources and bioavailability Claudine Manach, et al., The American Journal of Clinical Nutrition, Volume 79, Issue 5, May 2004, Pages 727–747, https://academic.oup.com/ajcn/article/79/5/727/4690182?login=true |
Cancer and flavonoids
Studies in animals and cells show that flavonoids may inhibit the cancer process by various mechanisms. However it is unclear whether these favourable effects also will occur in humans. A major reason is that these animal and cellular studies have been performed with high amounts of flavonoids, and it is questionable whether humans can cope with such high intakes. Epidemiological studies (studies in which the occurrence of a disease in a population is studied in relation to its risk factors) have not shown a protective effect of flavonoids on cancer, with the possible exception of lung cancer. These studies only included flavonols, flavones and catechins. For a proper evaluation of the role of flavonoids in cancer prevention more epidemiological studies are needed in especially with other subclasses of flavonoids. Cardiovascular and flavonoids Intake of flavonoids, especially flavonols and flavanones, has been favourably linked with a reduced risk of heart diseases such as myocardial infarction and with stroke. In particular consumption of tea, a rich source of flavonols and catechins, and a moderate consumption of wine was related to a lower risk of myocardial infarction in a couple of studies. Risk reductions of coronary heart disease of up to 65% were reported. In the epidemiological studies it was not possible to tell whether the effects were caused by the mentioned flavonoids or some other components in tea or wine. In the end, only intervention studies (a study where for example flavonoids are given to the participants and then it is monitored whether it has an impact on a disease) with pure flavonoids will be able to establish a protective effect of flavonoids in cardiovascular diseases. Neuro-degenerative diseases and flavonoids Dementia, Alzheimer’s disease and Parkinson’s disease are degenerative diseases which are becoming more common with the ageing population. A few epidemiological studies show that a moderate consumption of wine has a protective effect against dementia. Wine contains flavonoids called antocyanins and catechins. Such effect has not been observed for beer or spirits, thus pointing to an effect of flavonoids. Source: 1. Medicinal plants used against various inflammatory biomarkers for the management of rheumatoid arthritis S Singh, TG Singh, K Mahajan… - Journal of Pharmacy …, 2020 - Wiley Online Library https://onlinelibrary.wiley.com/doi/pdf/10.1111/jphp.13326 2. Chemistry and Biological Activities of Flavonoids: An Overview Shashank Kumar1 and Abhay K. Pandey https://www.hindawi.com/journals/tswj/2013/162750/ |
Resveratrol
Used in Japanese/Chinese medicine in an herbal product called Kojo-kon. It's primary active ingredient found in the plant polygonum cuspidatum, treats wide range of afflictions.
Video source:
Resveratrol: dosage and effect on cardiovascular health | David Sinclair https://www.youtube.com/watch?v=6vcF0C2cZI8 |
Image: https://phytochem.nal.usda.gov/phytochem/search/list
Dr. Duke's Phytochemical and Ethnobotanical databases facilitate in-depth plant, chemical, bioactivity, and ethnobotany searches using scientific or common names. |
References:
https://scholar.google.ca/scholar?hl=en&as_sdt=0%2C5&q=resveratrol&btnG= Resveratrol is apolyphenolic compound described as - 3, 5, 4-trihydroxystilbene - phytoalexin- produced by plants due to stress - plant antibiotic - stilbene compound (class of polyphenols) - fat soluble existing in cis, trans form - exist in glycone, aglycone form |
Resveratrol as many applications:
resveratrol and joint disease resveratrol cancer resveratrol ageing resveratrol review resveratrol alzheimer's resveratrol and Diabetis resveratrol and treatment resveratrol and effect resveratrol and cardiovascular resveratrol breast cancer resveratrol cataract .... |
Search example:
Resveratrol: CIS-RESVERATROL - Sprout Seedlings from Peanut; Groundnut. Vitis vinifera (Vitaceae) - Wine Grape; European Grape; Vid (Sp.); Weinrebe (Ger.); Vigne Vinifere (Fr.); Grape; Grapevine; Parra (Sp.) - Source: Fruit, Fruit Juice, steam, leaf,seed, pericarp *Note:(GMO products are engineered to be seedless = no-to-little benefit) |
What Did You Eat Yesterday?
The answer may sum up the reason why the Rheumatoid Arthritis is in it's current state. A diet high in fructose corn syrup, most definitely is causing a great deal of inflammation while the processed animal fats may cause nodules but it maybe due to the consumption of chemicals listed on the back of the processed products.
An overly rich diet confuses the immune system, It responds by triggering an inflammatory reaction, especially in fatty tissues. Our fat masses release substances that then propagate this inflammation throughout the body.(1)
On the other hand, those who are consuming diets, high in fruits, vegetable, nuts, seeds, just about anything that is grown and not processed will be experiencing less symptoms.
But if you are wondering what foods are causing havoc within your body or what
An overly rich diet confuses the immune system, It responds by triggering an inflammatory reaction, especially in fatty tissues. Our fat masses release substances that then propagate this inflammation throughout the body.(1)
On the other hand, those who are consuming diets, high in fruits, vegetable, nuts, seeds, just about anything that is grown and not processed will be experiencing less symptoms.
But if you are wondering what foods are causing havoc within your body or what
- Metabolic food reactions are due to inborn or acquired errors of metabolism of nutrients, such as in lactase deficiency, phenylketonuria and favism.
- Pharmacological reactions are generally due to low-molecular-weight chemicals which occur either as natural compounds, such as salicylates and amines, or to food additives, such as preservatives, colouring, emulsifiers and taste enhancers. These chemicals are capable of causing drug-like (biochemical) side effects in susceptible individuals.[5]
- Gastro-intestinal reactions can be due to malabsorption or other GI Tract abnormalities.
- Immunological responses are mediated by non-IgE immunoglobulins, where the immune system recognises a particular food as a foreign body.
- Toxins may either be present naturally in food, be released by bacteria, or be due to contamination of food products.[5] Toxic food reactions are caused by the direct action of a food or substance without immune involvement.[5]
- Psychological reactions involve manifestation of clinical symptoms caused not by food but by emotions associated with food. These symptoms do not occur when the food is given in an unrecognizable form.[5]
Food Allergy
When you are allergic to a certain protein that’s in a food item, your body’s immune system is mistaking that protein for a foreign invader, like a virus or bacteria,
Your body’s immune system automatically sends out or releases chemicals to fight off this protein (foreign invader, like a virus or bacteria), and the chemical that is released causes your body to break out in hives or cause an allergy reaction. Food allergies have increased more than 50% since 1997 and they've been linked to the modern lifestyle, so-called hygiene hypothesis, and overuse of antibiotics thus destroying the microbiota. Food allergies can be life-threatening.
In sensitive individuals, allergic reactions can be triggered by food proteins in gluten-containing cereals, crustaceans, fish, eggs, peanuts, soybean, milk, nuts, celery, mustard, sesame, lupin and molluscs. For example, gluten, a protein present in wheat, rye and barley and many other cereals, can trigger coeliac disease, a life-long systemic autoimmune disorder. For individuals with food allergies, the avoidance of allergenic foods, and gluten-free diet in those affected by coeliac disease, represent the conventional management of these conditions (EFSA 2014).(1)
Sarcopenia is the loss of skeletal muscle mass, strength and function, associated with aging.(2) Suboptimal protein intake has been related to sarcopenia, a condition characterized by loss of skeletal muscle mass and function (Deer RR. 2015, Bauer et al. 2013).
Your body’s immune system automatically sends out or releases chemicals to fight off this protein (foreign invader, like a virus or bacteria), and the chemical that is released causes your body to break out in hives or cause an allergy reaction. Food allergies have increased more than 50% since 1997 and they've been linked to the modern lifestyle, so-called hygiene hypothesis, and overuse of antibiotics thus destroying the microbiota. Food allergies can be life-threatening.
In sensitive individuals, allergic reactions can be triggered by food proteins in gluten-containing cereals, crustaceans, fish, eggs, peanuts, soybean, milk, nuts, celery, mustard, sesame, lupin and molluscs. For example, gluten, a protein present in wheat, rye and barley and many other cereals, can trigger coeliac disease, a life-long systemic autoimmune disorder. For individuals with food allergies, the avoidance of allergenic foods, and gluten-free diet in those affected by coeliac disease, represent the conventional management of these conditions (EFSA 2014).(1)
Sarcopenia is the loss of skeletal muscle mass, strength and function, associated with aging.(2) Suboptimal protein intake has been related to sarcopenia, a condition characterized by loss of skeletal muscle mass and function (Deer RR. 2015, Bauer et al. 2013).
Food Intolerance
One must differentiate food allergy (IgE-mediated) from food intolerance that can be cause for a variety of etiology including malabsorption (1), and celiac disease in which the gluten intolerance is due to the glysophates sprayed on the wheat before harvesting. food intolerance isn't usually life-threatening.
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Symptoms of a food intolerant, indicates an intolerant to that specific sugar (see bottom of page) and the body's inability to or has problems digesting that sugar:
Joint Inflammation Sugar causes inflammation,
Sugar intolerances can cause joint pain and inflammation (which is an underlying factor in most chronic diseases). |
Bloating
if your body is struggling to digest a particular sugar, it can cause you to bloat as that sugar tries to make its way through your digestive system, |
Anxiety - anxiety could indicate that your body isn't handling an influx of sugar
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Excess gas taking medications that help alleviate gas might help mitigate the problematic symptom, but it won't help with the underlying intolerance
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Stomach Ache - cramping is never ever comfortable — or easy to ignore. Sugar intolerances like lactose intolerance, can cause intense stomach cramping, if it’s an issue with glucose regulation, then eating sugar as part of a meal containing fat and protein will slow down the absorption of sugar in the intestinal tract.
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Not Sleeping Well - a sugar intolerance can also cause you to experience night sweats.
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Nauseous - nausea can also be indicator that you have a sugar intolerance, especially when paired with gas/bloating.
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Crash After Eating
- major energy dips after you eat sugar might also indicate that your body isn't handling it well. If this is your only symptom, it doesn't necessarily mean for sure that you have a sugar intolerance, but it could be an initial hint that something else is going on. |
Food Intolerance Home Test: FoodMarble Aire $250(+/-) https://foodmarble.com/
A tiny, portable, breathalyzer that determines your food intolerances, based on the same technology used by doctors and hospitals.
Product Reviews FoodMarble Aire hands-on reviewOne breath into this device could change what you eat foreverBy Andy Boxall https://www.digitaltrends.com/gadget-reviews/foodmarble-aire-review/ |
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"...If you decide to do these tests it is pretty arduous process and you have to really commit to it. You have to fast for 12 hours before, so do it overnight and then you would ...." See more apps/monitors/devices: https://wlcollins.weebly.com/the-medical-futurist.html |
Celiac Disease
The prevalence of celiac disease in patients with juvenile chronic arthritis is increased in patients with JCA.(2) Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci between both diseases. Celiac disease blood test can identify IgA or even IgG antibodies against gliadin. For reasons that aren’t well understood, a small amount of the patients are IgA deficient, meaning they aren’t able to produce any IgA antibodies (*), (1) in general, so in this case they’d need to have an IgG screening test done. (*) Exposure to Gonorrhea, tuberculosis, S. pneumoniae, E. coli, salmonella (14) in Blood type 'B' can wipe out the IgA antibodies. |
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What occurs in patients with celiac disease?
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Cannot tolerate the ingestion of gliadin and gluten and are toxic to the mucosa of the small intestine causing pathologic lesions. Treatment is abstaining from wheat.
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What causes production of gliadin anti-bodies (IgA)?
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Gliadin and Gluten Proteins causing direct mucosal damage of the small intestine. Detected in the blood of patient's with malabsorption.
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What are interfering factors that can elevated gliadin anti-bodies?
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Crohn's Disease, Colitis, Severe Lactose Intolerance
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What are the two criteria needed for a diagnosis of celiac disease?
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1. Characteristic Intestinal Lesion, 2. Symptoms improved with gluten-free diet
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What are the indications of Anti-Gliadin/IgA test?
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Test used to diagnose celiac disease and sprue by identifying antibodies to gliadin and gluten in affected patients.
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RA Diet
Eliminating sugar/fructose and most grains Optimizing your gut flora with the use of high potency fermented vegetables and/or probiotics Eating unprocessed, high-quality foods, organic and locally- grown if possible Eating your food as close to raw as possible Getting plenty high-quality animal-based omega-3 fats, such as krill oil |
(OA)
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(OA) and (RA)
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(RA)
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(RA)
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Gout
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GOT MILK ... hellno
The first thing most people think of when they hear calcium is “milk.” This is mainly because the American dairy industry heavily promotes the consumption of milk as a human’s sole source of calcium. What they often fail to let people know is that there are many other excellent sources of calcium.
Source: http://thenaturalhealthpage.blogspot.com/2013/10/plant-foods-rich-in-calcium.html
Calcium is a major material used by the body for mineralization of bones and teeth. It is also used in many different cellular processes such as nerve and muscle function and blood clotting. When dietary calcium is too low, calcium is leaked from the bones, and is instead used for functions required for survival. This, in turn, makes our bones weak and brittle.
The recommended daily calcium intake for adults aged
Diet’s high in protein, particularly animal protein, result in higher calcium loss in urine, which may be directly correlated to increased fracture risk. Eating a lower protein diet, rich in fruit and vegetables, will ensure your body is absorbing the minerals and vitamins from your food, instead of having these minerals stripped from your bones to be used or excreted elsewhere. |
Below is a list of plant foods (including but not limited to many others), that contain ample amounts of calcium:
1. Chia seeds (2 ounces = 600 mg)
2. Sesame seeds (1 tbsp = 90 mg) 3. Kohlrabi (1 cup = 390 mg) 4. Almonds (1/4 cup = 94 mg) 5. Collards (1 cup = 357 mg) 6. Spinach (1 cup = 250 mg) 7. Turnip greens (1 cup = 249 mg) 8. Brazil nuts (1/4 cup = 55 mg) |
9. Kale (1 cup = 179 mg)
10. Broccoli (1 cup = 178 mg) 11. Bok choy (1 cup = 158 mg) 12. Okra (1 cup = 135mg) 13. Pumpkin seeds (55 mg per 100 grams) 14. Butternut squash (1 cup = 84 mg) 15. Green Beans (1 cup = 58 mg) 16. Mulberries (1 cup = 55 mg) |
17. Celery (1 cup = 54 mg)
18. Cabbage (1 cup = 50 mg) 19. Artichoke (1 artichoke = 40 mg) 20. Gooseberries (1 cup = 38 mg) 21. Onions (1 cup = 36 mg) 22. Brussels sprouts (1 cup = 36 mg) 23. Asparagus (1 cup = 28 mg) 24. Avocado (1 avocado = 18 mg calcium) 25. Coconut meat (1 cup = 11 mg) |
How plant based diets can help people with rheumatoid arthritis
4 Oct 2019 ... A new review of specialist literature shows that following a plant based diet can reduce rheumatoid arthritis symptoms, and explains why.
4 Oct 2019 ... A new review of specialist literature shows that following a plant based diet can reduce rheumatoid arthritis symptoms, and explains why.
BodBot All of your nutrition targets are tailored to your specific goals and body. The nutrition requirements of gaining muscle, improving health, or optimizing athletic performance are all very different, and BodBot will recommend both macro and micronutrient targets accordingly.
https://www.bodbot.com/Nutrition/Foods/11231/jute-potherb-raw |
HappyForks is a comprehensive tool to manage your diet. It monitors your diet for several dozens of nutrients important for your health. This means more than calories and basic macro-nutrients. HappyForks takes into consideration individual nutrition requirements adjusted to your specific profile and objectives. From diet analysis through Nutrition Reports, Food Diary, Recipe analyzer, and database of your recipes - these features are designed to assist you in managing your diet effectively and reaching your goals.https://happyforks.com/food/jute/4017
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- Apple Cider Vinegar and Water - Apple cider vinegar has numerous health benefits. Among them, it helps reduce pain and inflammation in RA patients. Mix a small amount in a glass of water and drink daily.
- Peroxide - Peroxide can help treat RA symptoms. Just be sure you’re using special food-grade peroxide to help reduce the inflammation.
- Dark chocolate as bioflavonoids
In his video, Dr Peter D’Adamo states:
"When we get sick we have inflammation or chronic disease our process of making these glycoproteins and glycolipids becomes disrupted and so we start to get changes in the sugar profile of the tissues that are involved in that particular disease and it turns out that like I said before since the glycosylation process acts like a zip code that very often these cells will start to behave in very odd ways." 43:23 |
Glyconutrients (2/2) - Lukas Waldmann
https://www.youtube.com/watch?v=8_fjs6iZ5IU The World Foundation for Natural Science Published on Mar 13, 2017 Glyconutrients are the real sugars, healthy ones! What is more: Glyconutrients are absolutely essential for every cell in our organism. Without them there is no accurate communication and no regulated biochemical reactions between the body's cells. Only when communication at the cellular level functions unobstructed is our body capable of delivering its self-healing powers and sustaining its own health. Lukas Waldmann, Naturopath, Rotkreuz, Switzerland at the 21st International "New Scientific Outlook" World Congress 2016, Ulm, Germany, 04.11.2016 |
Paeonol
Effect of Paeonol on Proliferation and Apoptosis of Human Rheumatoid Arthritis Synovial Fibroblasts
赵俊云杨向竹郭健
北京中医药大学
Objective: To investigate the effect of paeonol on the proliferation and apoptosis of human rheumatoid arthritis synovial fibroblasts. Methods: The human rheumatoid arthritis synovial fibroblast cell line MH7 A was used as the research subject. The effect of paeonol on the proliferation of MH7 A cells was detected by MTT assay. The effect of paeonol on the apoptosis of MH7 A cells was examined by flow cytometry. The mRNA levels of Ki-67 and Caspase-3 were measured by qRT-PCR and the protein levels were checked by Western blot method. Results: Paeonol had an inhibitory effect on the proliferation of MH7 A,and the inhibition rate was positively correlated with dose and duration. The apoptosis of MH7 A was significantly increased after 72 hours of intervention of paeonol. The expression of Ki-67 was significantly decreased and the expression of Caspase-3 was significantly increased. Conclusion: Paeonol can inhibit the proliferation of MH7 A by decreasing the expression of Ki-67 and induce the apoptosis of MH7 A by promoting the expression of Caspase-3. (1), (2), (3)
A number of biological effects of paeonol in vitro or in animal models have been observed. Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease.[7] Paeonol also reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats.[8]
Paeonol shows antimutagenic activities.[2][5] It also has anti-inflammatory and analgesic effects in carrageenan-evoked thermal hyperalgesia.[9] Paeonol inhibits anaphylactic reaction by regulating histamine and TNF-α.[10]
Paeonol has MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively.[11]
Table below lists some sources of Paeonol:
赵俊云杨向竹郭健
北京中医药大学
Objective: To investigate the effect of paeonol on the proliferation and apoptosis of human rheumatoid arthritis synovial fibroblasts. Methods: The human rheumatoid arthritis synovial fibroblast cell line MH7 A was used as the research subject. The effect of paeonol on the proliferation of MH7 A cells was detected by MTT assay. The effect of paeonol on the apoptosis of MH7 A cells was examined by flow cytometry. The mRNA levels of Ki-67 and Caspase-3 were measured by qRT-PCR and the protein levels were checked by Western blot method. Results: Paeonol had an inhibitory effect on the proliferation of MH7 A,and the inhibition rate was positively correlated with dose and duration. The apoptosis of MH7 A was significantly increased after 72 hours of intervention of paeonol. The expression of Ki-67 was significantly decreased and the expression of Caspase-3 was significantly increased. Conclusion: Paeonol can inhibit the proliferation of MH7 A by decreasing the expression of Ki-67 and induce the apoptosis of MH7 A by promoting the expression of Caspase-3. (1), (2), (3)
A number of biological effects of paeonol in vitro or in animal models have been observed. Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease.[7] Paeonol also reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats.[8]
Paeonol shows antimutagenic activities.[2][5] It also has anti-inflammatory and analgesic effects in carrageenan-evoked thermal hyperalgesia.[9] Paeonol inhibits anaphylactic reaction by regulating histamine and TNF-α.[10]
Paeonol has MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively.[11]
Table below lists some sources of Paeonol:
Fiber
foods that really increase diversity and increased motility and health of gut
bacteria so fundamentally it's fiber so the more plant plant-based foods you eat the better is the general consensus We're calling something gluten when we should be calling it lectin. There's probably about four to six percent of the protein content of wheat for instance is wheat germ agglutinin it is not a gluten gluten is its own thing but it is a lectin and as a being elected it will cause potential for inflammatory reactions because of that agglutination phenomenon and so essentially what we have a case here a classic case of mistaken identity and that oftentimes when people are attributing a benefit to going gluten-free they may have not realized it but if indeed gluten wasn't their problem they got the benefit from going lectin free and in essence basically managed to see that it was gluten because that was the things that they were looking for and there's crossover between the two |
Wider ScopeShanidar III – A Neandertal who ate his veggies… Or at least chewed them
https://anthropology.net/2008/04/28/shanidar-iii-a-neandertal-who-ate-his-veggies-or-at-least-chewed-them/ One last thing, if Shanidar 3 really was eating plants, did his foot injury have anything to do with this? See, Shanidar III has a degenerative joint disorder in his foot. That woulda caused a lot of pain and limited his mobility. Would that have anything to do with why he was chewing on sedentary food sources?
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Research Progress of Traditional Chinese Medicine Treatment of Rheumatoid Arthritis
李冀李想高彦宇
黑龙江中医药大学 Abstract:Rheumatoid arthritis(RA)is a chronic systemic autoimmune disease associated with progressive disability,premature death,and socioeconomic burdens. The main pathological changes were synovial cell proliferation,synovitis,cartilage injury and bone erosion. The rate of disability is high,which is very harmful to human health and is difficult to cure. With the deepening of modern research,doctors use traditional Chinese medicine to treat RA has accumulated rich clinical experience and played a good effect. In this paper,the literature on the treatment of RA with traditional Chinese medicine was reviewed,and the mechanism of treatment was reviewed.
http://new.oversea.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDTEMP&filename=LZXB201912001&v=Mjk2OTVtVWIvTUtUZlRiTEc0SDlqTnJZOUZaWVI4ZVgxTHV4WVM3RGgxVDNxVHJXTTFGckNVUkxPZVplUnRGaUQ= |
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Jute, potherb, raw
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On Professor LIU Jian’s Medication Rules in Treating Rheumatoid Arthritis Based on Association Rule and Cluster Analysis
Abstract:Objective:To analyze Professor LIU Jian’s medication rules in the treatment of rheumatoid arthritis using association rules and cluster analysis.Methods:A total of 4600 prescriptions from Professor Liu Jian for rheumatoid arthritis were collected,and the database was established by Excel 2015 to summarize the data and analyze the frequency.SPSS 23.0 and SPSS Modeler 14.2 were used for data mining.Results: ① Four categories of medicinals were commonly used by Professor LIU Jian(most of them with frequency up to 50%),i.e.medicinals of invigorating spleen and removing dampness,medicinals of clearing away heat and toxin,medicinals of promoting blood circulation and removing blood stasis,medicinals of removing wind and dampness. ② According to the association rules,the drug combinations with higher confidence and association were Honghua(Flos Carthami)and Taoren(Semen Persicae),Pugongying(Herba Taraxaci)and Baihuasheshecao(Herba Hedyotis Diffusae),Chenpi(Pericarpium Citri Reticulatae)-Jiangbanxia(Rhizoma Pinelliae Praeparatum). ③ Cluster analysis showed that there were five groups:Honghua(Flos Carthami),Taoren(Semen Persicae),Fuling(Poria),Chenpi(Pericarpium Citri Reticulatae),Danshen(Radix et Rhizoma Salviae Miltiorrhizae),Gancao(Radix et Rhizoma Glycyrrhizae),Yiyiren(Semen Coicis),Pugongying(Herba Taraxaci),Weilingxian(Radix et Rhizoma Clematidis),Shanyao(Rhizoma Dioscoreae),Xixiancao(Herba Siegesbeckiae),Baihuasheshecao(Herba Hedyotis Diffusae),Zexie(Rhizoma Alismatis);Jixueteng(Caulis Spatholobi);Maiya(Fructus Hordei Germinatus),Rendongteng(Caulis Lonicerae Japonicae);Duzhong(Cortex Eucommiae),Baizhu(Rhizoma Atractylodis Macrocephalae),Huangqin(Radix Scutellariae);Jiangbanxia(Rhizoma Pinelliae Praeparatum).Conclusion:Professor Liu Jian’s treatment for rheumatoid arthritis has distinct characteristics,emphasizing treating the spleen,combining medicinals of promoting blood circulation and removing blood stasis,medicinals of clearing heat and detoxification,and medicinals of eliminating wind and dampness,regulating the liver,spleen and kidney,correcting deficiency and excess,and targeting the root causes and symptoms simultaneously.
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Jacobus Houbraken, born Dec. 25, 1698, Dordrecht, Holland - died Nov. 14, 1780, Amsterdam, was the leading portrait engraver in 18th-century Holland. The son of the painter and art writer Arnold Houbraken, he settled in Amsterdam in 1707, and during his lifetime he engraved 400 portraits after paintings by contemporary Dutch painters.
As gouty or arthritic attacks, or gout in the narrower sense (arthritis, literally translated: joint inflammation), are first called certain inflammatory and painful affections of the joints, which are peculiar and later leave earthy concretions as products of disease, and as their internal cause peculiar nutritional anomaly or dyscrasia is different. This gouty dyscrasia or gout disease, also generally called gout, develops from indigestion and abdominal plethora, is closely related to hemorrhoidal and stone disease, and appears to consist in an excess of connate but undecayed animal matter, chiefly in the form of urate Salts, circulated in the ???? and deposited in periodic inflammatory attacks on the joints and other fibrous hides. One differentiates between an acute and a chronic, a regular and irregular form of gouty work (the former likes to pass on to the latter later); As reported gout one refers to various other disease states, if one can assume that behind them a similar dyscrasia is hidden. Read More: Ludwig Choulant ... Textbook of Special Pathology and Therapy of Humans,
By Johann Ludwig CHOULANT
Johann Wessel, c1740s? Creator: Jacobus Houbraken
As gouty or arthritic attacks, or gout in the narrower sense (arthritis, literally translated: joint inflammation), are first called certain inflammatory and painful affections of the joints, which are peculiar and later leave earthy concretions as products of disease, and as their internal cause peculiar nutritional anomaly or dyscrasia is different. This gouty dyscrasia or gout disease, also generally called gout, develops from indigestion and abdominal plethora, is closely related to hemorrhoidal and stone disease, and appears to consist in an excess of connate but undecayed animal matter, chiefly in the form of urate Salts, circulated in the ???? and deposited in periodic inflammatory attacks on the joints and other fibrous hides. One differentiates between an acute and a chronic, a regular and irregular form of gouty work (the former likes to pass on to the latter later); As reported gout one refers to various other disease states, if one can assume that behind them a similar dyscrasia is hidden. Read More: Ludwig Choulant ... Textbook of Special Pathology and Therapy of Humans,
By Johann Ludwig CHOULANT
Johann Wessel, c1740s? Creator: Jacobus Houbraken
Gout (podagra) -Due in part to excessive fat in the diet, excessive use of alcohol, and other irritating stimulants. Defective elimination and sluggishness of the entire system due to the lack of exercise, high living, emotional/physical stress, and errors in the diet are responsible for this rheumatic condition. Most commonly found in the big toe but can affect any joint. (DIY, test – under Ruban)
High in fish - contains mercury
High in fish - contains mercury
How an infection affects Diabetes Dr.BiswaroopRoyChowdhury
Infection (cold, flu) causes a stress response in the body by increasing the amount of certain hormones such as cortisol and adrenaline. In Diabetes, these hormones work against the action of insulin and, as a result, the body’s production of glucose increases, which results in high blood sugar levels. When your blood sugar is high, the white cells in your body are unable to “mop up” bacteria because they cannot move around at their normal speed and do not reach the infection site quickly enough to engulf and kill the bacteria. In a person who does not have diabetes, extra insulin is produced to counter these effects, but this is not possible for someone with diabetes, and so hyperglycemia persists and ketoacidosis can occur.. |
Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia).
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Diabetes Reversal by a Plant-Based Diet plays an important role in controlling blood sugar level (1). In two separate studies low carbohydrate diet successfully decreased or sometime even eliminated the need for medicine 6,7. On the contrary, high fat diet results in the impairment of glucose level by altering binding of insulin at its receptors. The type of fatty acid changes phospholipids composition thereby changing membrane fluidity and insulin signaling 8.
https://biswaroop.com/wp-content/uploads/2019/05/JETIR1905867_Reduction-in-drug-dosage_Dr.BiswaroopRoyChowdhury.pdf
https://biswaroop.com/wp-content/uploads/2019/05/JETIR1905867_Reduction-in-drug-dosage_Dr.BiswaroopRoyChowdhury.pdf
if you get the rubella vaccine of course it can cause acute and chronic arthritis and women
Apoptosis which is cell death of rheumatoid
arthritis synovial cells are the cells that damage the synovial membrane, it kills them.
You can have a piece of Gouda cheese over your fermented sauerkraut and you kill the cells that are damaging your joints if you have rheumatoid
arthritis.
Diet lead to changes in inflammation, inflammatory markers changes in gene expression and those they to potential changes in our metabolisms and then there's a feedback so those changes are you back through that chain and then potentially change microbes we have and it just goes around comes around.
Types of Sugar
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Granulated
-Purified sucrose from cane or beets -Dissolves quickly Brown sugar -crystallizing sucrose from molasses syrup -coating granulated in cane molasses Honey 40.5% fructose, 34.5% glucose, < 8% sucrose+water Maple Syrup Mainly sucrose, 35% water Corn Syrup -Pure sugar, Liquid, made from dextrins+maltose+glucose -Hydrolyzing corn starch with acid and heat/enzymes
High Fructose Corn Syrup Corn syrup that has part of the glucose turned into fructose
-Ground up sugar crystals into powder -Need to add corn starch to prevent caking Molasses -Mixture of mostly sucrose with some glucose and fructose -Removed at intermediate stage of refining cane syrup to sugar |
Glucose
"blood sugar" fruit, veggies, and grains
"Table sugar" table sugar and sugar cane
"Fruit Sugar" fruit
"Malt Sugar" grains
"Milk sugar" milk
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Honey
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Generally Honey
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Argentina Honey
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The chemistry of honey also varies depending upon the geography and purity of the sample. There is no standard scale globally. However, generally honey has a content of
Premium Mānuka honey is a monofloral honey produced from the nectar of the mānuka tree, Leptospermum scoparium. The honey is commonly sold as an alternative medicine, certified Kosher and Halal.
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Beside these other components are also found in minor concentration. The trace elements of honey were determined in mg kg−1 as following:
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Cantarelli et al. (2008) analyzed different varieties of honey from different parts of Argentina. They identified a vast range of trace elements in different samples of honey. The major trace elements in μg g−1 of honey were:
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How a high sugar diet can harm your health.
1. At risk of obesity
2. (Lead to) Type two diabetes 3. High blood pressure 4. Risk for heart disease or stroke 5. Also linked to depression, fatigue, anxiety, poor concentration and mood swings 6. Causes dental decays, dental caries, and gum disease Natural sugar Naturally occurring sugars such as those contained in fruits, veggies, milk and other plants. Added sugar Sugars and syrups that are added to foods or beverages when they are processed or prepared. -Brown sugar -Corn sweetener -Corn syrup -High fructose corn syrup -Syrup -Sugar molecules ending in OSE Added sugars contribute additional calories and zero nutrients to food. |
The number of calories that children should eat between 6 and 12 years old is 1,600 to 2,200 per day, depending on how active they are. During puberty, boys may need as many as 2,500 to 3,000 calories per day, especially if they are very active. (1)
Video: How to Find Maintenance Calories. TEE (Total Energy Expenditure) Daily Caloric Needs https://www.youtube.com/watch?time_continue=166&v=VbFJzkdVOWs&feature=emb_title |
The maximum amount of added sugars you should eat in a day
(1) https://kidshealth.org/en/kids/calorie.html
(2) https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/sugar/added-sugars (3) https://www.who.int/publications-detail/9789241549028 (4) https://www.aapd.org/research/oral-health-policies--recommendations/dietary-recommendations-for-infants-children-and-adolescents/ How to Count Your Sugar Intake: 11 Steps (with Pictures) ...https://www.wikihow.com/Count-Your-Sugar-Intake |
if you have excess fat in your body if you drink honey with warm water it breaks down the fat in the system if you drink it with cold water it will give you weight. STOP EATING IT! 99% of People Thinks is Medicine, But It Hurts YOU www.youtube.com/watch?v=VBEOjcUDeFM |
A Novel Approach for Treating RA With a 60-90 Percent Likelihood of Improvement
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