Peter Paul Rubens Nassau-Dillenburg 1577–1640 Netherlands (d. Age 63)
Unlike Gout, Arthritis mainly affected the poor, affected women more often than men, and had previously been ignored by other physicians who concerned with earning acclaim and compensation for their work usually chose to treat more affluent patients.
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Carpal coalition
Carpal coalition is the abnormal fusion of two or more carpal bones when they fail to segment during intrauterine development. First described by Eduard Sandifort in 1779, carpal coalitions are often an isolated issue which connect two carpal bones in the same row of the wrist. These issues are congenital and occur at various rates throughout the population....Carpal coalition - Wikipedia 100 BODIES found in York.: Two skeletons wit fused bones. Among the skeletons were two sets of remains which showed signs of severe disfigurement. The hand bones of one were fused together while the second had more severe bone fusions in an arm and leg. https://www.facebook.com/watch/?v=812197245981504 All Documentary, August 6, 2020 · After 100+ skeletons are found in 10 mass graves the truth must be unsurfaced! |
Sarcopenia; the age-associated loss of skeletal muscle mass, muscle strength, and physical performance [8].
The European Society for Clinical Nutrition and Metabolism (ESPEN) expert groups recommend that healthy older adults consume at least 1.0–1.2 g of protein per kilogram bodyweight per day (g/kg BW/d) to maintain muscle mass [12,17], which is in contrast to the lower recommended dietary allowance of 0.8 g/kg BW/d for healthy adults [18]
The European Society for Clinical Nutrition and Metabolism (ESPEN) expert groups recommend that healthy older adults consume at least 1.0–1.2 g of protein per kilogram bodyweight per day (g/kg BW/d) to maintain muscle mass [12,17], which is in contrast to the lower recommended dietary allowance of 0.8 g/kg BW/d for healthy adults [18]
The Joints: Structure and function.
Individual bones meet at joints or junctures where movement is permitted. Depending on the range of joint movement, some are simple, some are more involved.
A joint consists of an articular capsule, articulating surfaces and an articular cavity. A small amount of lubricating fluid is found inside the articular cavity that aids joint movement. When the joint is inflamed, this fluid may increase and become purulent. When this is serious, the articular surfaces become rough, to affect joint movement, When strong force is exerted on a joint, this may be serious enough to cause dislocation of the joint and affect its movement.
Individual bones meet at joints or junctures where movement is permitted. Depending on the range of joint movement, some are simple, some are more involved.
A joint consists of an articular capsule, articulating surfaces and an articular cavity. A small amount of lubricating fluid is found inside the articular cavity that aids joint movement. When the joint is inflamed, this fluid may increase and become purulent. When this is serious, the articular surfaces become rough, to affect joint movement, When strong force is exerted on a joint, this may be serious enough to cause dislocation of the joint and affect its movement.
Classic Changes in Advanced RA
VOLAR PLATE INJURIES
PIP 4 Way Resistance Challenge to test for four ligamentous stability for the PIP joint |
Collateral ligaments are found on either side of each finger and thumb joint, they prevent abnormal sideways bending of each joint.
Volar or Palmar Plate is a thick ligament which joins together two bones, they reinforce the joint capsules, enhance joint stability, and limit hyperextension. The plate can loosens from disease or injury causing a swan neck deformity. |
Xray imaging in non inflammatory arthritis
Sports related UCL Injury
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Elbow Ligament Injury
Treatment for
Medial ulnar collateral ligament (UCL) injury
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MEDIAL ULNAR COLLATERAL LIGAMENT INJURY
Can a torn ligament in elbow heal itself?
You may need a splint or a sling for several weeks to keep your elbow from moving while it heals. If the ligament is completely torn, you may need surgery to repair it. ... The pain often gets better within a few weeks with self-care, but some injuries may take several months or longer to heal. |
Mallet finger
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Trigger Finger/Thumb: causes
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Trigger finger (tenosynovitis)
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Dupuytrens Contracture
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Dupuytrens Contracture
Trigger finger is not the same as Dupuytren's contracture. They are only similar in that both involve finger flexion.
The presence of rheumatoid hand deformities, especially flexion and ulnar deviation of the metacarpophalangeal joints may mask the flexion deformity caused by Dupuytren's contracture. The result of contraction of the palmar fascia due to some slight injury, pressure, strain, or to gout..
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Dupuytrens Contracture
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Thumb Deformity "Z" Thumb |
Jaccoud arthropathy and Z thumb
Jaccoud arthropathy, is a chronic non-erosive reversible joint disorder that may occur after repeated bouts of arthritis. It is caused by inflammation of the joint capsule and subsequent fibrotic retraction, causing ulnar deviation of the fingers, through metacarpophalangeal joint subluxation, primarily of the ring and little-finger.
It has been reported to occur after attacks of acute rheumatic fever, it resembles rheumatoid arthritis but with less overt inflammation, and rheumatoid factor is absent. |
Jaccoud arthropathy
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Swan Neck Deformity
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The Synovial Fluid
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Boutonniere Deformity
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The synovium is the lining of the joint which produces a clear liquid substance known as synovial fluid, it is responsible for lubricating healthy joints and gives cartilage and bones the nourishment required to remain effective and mobile.
Once RA has been triggered, antibodies are produced and they go into attack mode. These antibodies release chemicals that cause inflammation to the synovium, inhibiting its ability to produce the synovial fluid. As less and less fluid is produced, the joints become more stiff and immobile. As the synovium becomes thicker without the benefit of the fluid’s normal, healthy lubrication, the joint’s cartilage can also become destroyed, causing inflammation. Over time, this can weaken and eventually destroy the connective tissue between the bones. Once the cartilage is destroyed, the ligaments that connect to the bone also begin to weaken. As the ligaments and tendons weaken, they can no longer hold joints in proper position; they’ve essentially been stretched out, which can cause such a severe loss of configuration that the joint can eventually be totally destroyed. |
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ulnar deviation and palmar subluxation
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Factors that Increase ulnar deviation force
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Ulnar Drift
Swelling of the metacarpophalangeal joints causes the fingers to become displaced to the ulnar side.
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Heberden's nodesHeberden's nodes are higher up on the DIP finger and are associated with osteoarthritis but in a study, 67% of patients with rheumatoid arthritis had probable Heberden's nodes. (1)
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Nodes
Heberden's and Bouchard's nodes in arthritis assessment (Rosen's 1510) are osteophytic spurs found on the hands.
Heberden’s nodes are caused by the formation of osteophytes due to repeated trauma at the joint and usually occurs during middle age. Mucous cyst: small, fluid-filled sacs that form between the DIP joint of the finger and the bottom of the fingernail. Bouchard’s nodes are typically associated with limited motion of the affected joint.
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Bouchard's nodes
Bouchard's nodes are located in the PIP joints and seen in those with RA.
Brain Natriuretic Peptid (BNP) |
benign rheumatoid nodules
One of the most common skin-based symptoms of rheumatoid arthritis is the development of nodules. These rheumatoid nodules occur in about one-quarter of rheumatoid arthritis patients, both men and women and their severity can vary from patient to patient.
Not everyone with RA gets them. Doctors believe these things can make you more likely to get nodules:
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Nodules
Synovial osteochondromatosis is an uncommon condition characterized by the formation of multiple nodules of hyaline cartilage within the sub-synovial connective tissue. The differential diagnosis includes chronic articular infection, osteoarthritis, pigmented villonodular synovitis, mono-articular inflammatory arthritis and periarticular neoplasms like synovial sarcoma. The treatment of choice is excision of the synovium and removal of the loose bodies. The prognosis is good, but recurrences may occur if the removal is incomplete.
Dimethyl sulfoxide Dimethyl sulfoxide is an organosulfur compound with the formula2SO. This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high melting point. DMSO has the unusual property that many individuals perceive a garlic-like taste in the mouth after contact with the skin.More at Wikipedia Who Develops Rheumatoid Nodules?Most commonly, rheumatoid nodules develop in patients already living with rheumatoid arthritis for some time. They generally don’t precede other rheumatoid arthritis symptoms.
Research suggests that rheumatoid nodules are commonly found in patients who possess high levels of the protein rheumatoid factor, an antibody seen in a handful of autoimmune disorders. This may mean that the patients may require treatment with drugs in the class of immunomodulators, such as Methotrexate. Similarly, research has also shown an increased likelihood of developing nodules in rheumatoid arthritis patients who smoke, even though a direct link between smoking and the formation of rheumatoid nodules is still unclear. Accelerated NodulosisAccelerated nodulosis is a specific condition that occurs with rheumatoid nodules where patients experience the formation of multiple nodules in a centralized location typically on the fingers and backs of the hands. This is compared to the sporadic appearance of a few rheumatoid nodules that form in patients here and there. In many cases, physicians have found that accelerated rheumatoid nodulosis occurs in patients who are pursuing methotrexate therapy. |
Rheumatoid Nodules
ganglion
Semisolid or fluid-containing cyst that develops on a tendon, often in the wrist, hand, or foot. It is a rounded lump under the skin and may or may not be painful. Though it is rare, rheumatoid nodules are capable of forming on the vocal cords and also in the lungs, heart and other internal organs.
How to Treat Rheumatoid NodulesNodules that form on the heels or beneath the feet can be debilitating to the patient limiting their mobility.
Certain disease-modifying antirheumatic drugs (DMARDs) have been known to reduce the appearance of rheumatoid nodules. Other treatments like steroid injections can also help to decrease the size of rheumatoid nodules. Some patients report that even after treatment or having their rheumatoid nodules removed, they do grow back. Unfortunately, the nature of rheumatoid arthritis and its symptoms mean that the nodules can recur after treatment. |
Subcutaneous nodules
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Bursitis :
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The NECK PAIN C1, C2, C3
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All patients with a cervicomedullary angle less than 135° had evidence of brainstem compression, cervical myelopathy, or C2 root pain. Also, all patients with cervicomedullary junction compression were neurologically abnormal. MR was found to be as good as tomography in evaluating the atlantodental interval, dens erosion, ligamentous calcification or osteophytes of the upper spine, subaxial subluxation, and various subluxations that occur in the occiput-C2 area. MR was less effective than tomography in evaluating the basion-dental interval, erosion of the posterior spinous processes, apophyseal joint disease from C3 inferiorly, and cystic changes of the articular facets of C1–C2. The most clinically important parameters were well seen with MR. www.ajnr.org/content/9/3/565Source
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Neck
Cervical spine involvement occurs in about 90% of the patients with rheumatoid arthritis. All rheumatoid arthritis patients should have cervical spine examination. (1)
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Fascilitis
Inflammation of the fascia around a muscle. Inflammation of the fascia on the bottom of the foot that is caused by excessive running or exercise. There is aching or stabbing around the heal. https://www.youtube.com/watch?v=v54l3wDTJHg |
The Symptoms Associated with Ulnar Nerve Damage Include:
-a loss of sensation in your hand (ring and little fingers) -a loss of coordination in your fingers. -a tingling or burning sensation in your hand. -pain. -hand weakness that may get worse with physical activity. -a loss of grip strength. https://www.youtube.com/watch?v=d85QKyWvrbI |
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RA and Eyes
Rheumatoid arthritis can cause inflammation in the white part (sclera) of your eyes, which can
result in redness and pain. Uveitis can cause such symptoms as redness, blurred vision, sensitivity to light, pain, and “floaters” — or dark spots that seem to float in the eye. 25:43
Pilocarpine is a drug used to treat glaucoma derived from the plant Rutaceae Video Source: Taxonomy And Diversity Of Rutaceae https://www.youtube.com/watch?v=ck0aZaj37ys |
Tenosynovitis
Inflammation and pain due to overuse of a tendon and inability of the synovium to produce enough lubricating fluid. Other signs of RA disease activity:
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VTE
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Basic Science
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Clinical skills/Investigations
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Blood tests
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Rheumatic diseases include a variety of disorders involving synovial joints; among them:
Osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis are the most common
Osteoarthritis is characterized by degradation of articular cartilage and subchondral remodeling
Rheumatoid arthritis is a chronic systemic inflammatory disease that primarily involves synovial joints, especially small joints in the hand and feet.
Ankylosing spondylitis is characterized by chronic inflammation of the spine (including sacroiliac joints), a high percentage of enthesopathy, a tendency of familial aggregation, and association of human leukocyte antigen (HLA)–B27.
Osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis are the most common
Osteoarthritis is characterized by degradation of articular cartilage and subchondral remodeling
Rheumatoid arthritis is a chronic systemic inflammatory disease that primarily involves synovial joints, especially small joints in the hand and feet.
Ankylosing spondylitis is characterized by chronic inflammation of the spine (including sacroiliac joints), a high percentage of enthesopathy, a tendency of familial aggregation, and association of human leukocyte antigen (HLA)–B27.
Synovitis Synovitis is an inflammation of the joint lining (called the synovium) In some cases, the synovitis itself may be the cause of joint damage and be the main cause of joint pain and dysfunction. Diseases of the synovium, such as a number of rheumatologic diseases including rheumatoid arthritis and Systemic Lupus Erythematosus, cause injury to the joint are immune mediated. https://www.ypo.education/orthopaedics/general/joint-synovectomy-t179/video/ The Eclectic Medical Journal, Jan. 1906 (page 175)https://archive.org/details/eclecticmedical17unkngoog/page/n260 |
ENZYMES
Enzyme levels in synovial fluid have been studied extensively in humans and increases have been found to accompany various articular diseases. However, increases (or decreases) in specific enzymes that would allow a differentiation of one disease entity from another have not been demonstrable. Enzymes are released into the synovial fluid from damaged tissue during phagocytosis and from the general circulation about the inflamed joint. Although their diagnostic significance is not great, the role enzymes play in destruction of articular tissue is important. Of particular importance are the collagenases, which specifically break down collagen of articular cartilage. Collagenases have been found in various inflammatory synovial fluids and especially in synovial fluid of animals with rheumatoid arthritis, where they are produced by the synovial membrane cells and by the polymorphonuclear leukocytes.(9) These enzymes probably account for the invasive properties of rheumatoid pannus. |
chondroitin
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collagenase
enzyme
produced by bacteroides species catalyzes collagen degradation aka hydrolysis |
hyaluronidase
enzyme
produced by streptococcus titans produced by streptococcus salivarius destroys amorphous ground substance |
PROSTAGLANDINS
Prostaglandins are a family of compounds comprising 20 carbon aliphatic unsaturated fatty acids.(26) Although first described in 1933, it is only recently that their physiological significance has begun to be appreciated. In relation to articular disease, it is now known that prostaglandin E, (PGE-1) plays a significant role in aiding or promoting the tissue destruction of rheumatoid arthritis.(25,26) Synovial fluid levels of prostaglandins in human rheumatoid arthritis patients are elevated far beyond those in normal joint fluid or joint fluid from patients with osteoarthritis. In vitro studies have shown increased prostaglandin synthesis by rheumatoid synovium and the promotion of bone resorption and articular cartilage destruction by prostaglandins.(27)
To date, data are not available describing prostaglandin levels in synovial fluid from a large number of normal dogs or cats or in those with disease. However, increased amounts of prostaglandins have been found in the joints of dogs injected with known inflammation producing substances, suggesting that, as in humans, synovium of the canine joint produces prostaglandins when inflamed.(10) Prostaglandin levels of synovial fluid have no great diagnostic significance as yet, but they may prove to be valuable in differentiating early immune-mediated synovitis from the synovitis of osteoarthritis.
sjogren
https://www.youtube.com/watch?v=C3e6V0tZIA4
https://www.youtube.com/watch?v=xN6tHrp1LVw&feature=emb_logo
https://www.sciencedirect.com/topics/medicine-and-dentistry/rheumatic-disease
Prostaglandins are a family of compounds comprising 20 carbon aliphatic unsaturated fatty acids.(26) Although first described in 1933, it is only recently that their physiological significance has begun to be appreciated. In relation to articular disease, it is now known that prostaglandin E, (PGE-1) plays a significant role in aiding or promoting the tissue destruction of rheumatoid arthritis.(25,26) Synovial fluid levels of prostaglandins in human rheumatoid arthritis patients are elevated far beyond those in normal joint fluid or joint fluid from patients with osteoarthritis. In vitro studies have shown increased prostaglandin synthesis by rheumatoid synovium and the promotion of bone resorption and articular cartilage destruction by prostaglandins.(27)
To date, data are not available describing prostaglandin levels in synovial fluid from a large number of normal dogs or cats or in those with disease. However, increased amounts of prostaglandins have been found in the joints of dogs injected with known inflammation producing substances, suggesting that, as in humans, synovium of the canine joint produces prostaglandins when inflamed.(10) Prostaglandin levels of synovial fluid have no great diagnostic significance as yet, but they may prove to be valuable in differentiating early immune-mediated synovitis from the synovitis of osteoarthritis.
sjogren
https://www.youtube.com/watch?v=C3e6V0tZIA4
https://www.youtube.com/watch?v=xN6tHrp1LVw&feature=emb_logo
https://www.sciencedirect.com/topics/medicine-and-dentistry/rheumatic-disease
During the course of rheumatoid arthritis, the synovial tissue is infiltrated by immune cells that secrete large amounts of cytokines. This pro-inflammatory milieu leads to an up-regulation of integrin receptors and their ligands in the synovial tissue. As a consequence, integrin signaling is enhanced, leading to enhanced production of matrix-degrading enzymes and cytokines. Furthermore, in analogy to invading tumors, synovial fibroblasts start invading and degrading cartilage, thereby generating extracellular matrix debris that can further activate integrins.
Chemical changes in RA
Chemical changes occur when a substance combines with another to form a new substance, called chemical synthesis or, alternatively, chemical decomposition into two or more different substances. These processes are called chemical reactions and, in general, are not reversible except by further chemical reactions.Wikipedia, Biochemical and clinical changes in rheumatoid arthritis: Their relation to the action of antirheumatoid drugs J.S.Dixon |
Haematological changes in RA
Hematologic diseases are disorders which primarily affect the blood. Hematology includes the study of these disorders.Wikipedia |
Serological changes in RA
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection, against other foreign proteins, or to one's own proteins.Wikipedia |
Avascular Necrosis
Osteonecrosis is most common in the hip, but also seen in the humerus, knee, and talus and more rarely seen in the smaller bones of the wrist such as the lunate[1] or scaphoid.
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2. Non-traumatic
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.Avascular necrosis/Osteonecrosis is a degenerative bone condition characterised by death of cellular components of bone secondary to an interruption of the subchondral blood supply.
It can be caused by trauma or non traumatic events and is seen in gout, diabetes. |
It typically affects the epiphysis of long bones at weight-bearing joints. Advanced disease may result in subchondral collapse which threatens the viability of the joint involved. Non-traumatic cases will typically present with mechanical pain of variable onset and severity and often difficult to localize. In early disease, the physical examination is often normal which inevitably causes a delay in diagnosis.[1]
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Why we develop
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Rheumatoid Arthritis: The Infection Connection - Part 1
After a fall downstairs,she seriously injured both ankles and they didn't heal in a reasonable amount of time and my family doctor was puzzled he sent me to a Rheumatologist he ran a bunch of tests they revealed that I had rheumatoid arthritis.
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Autoimmune Disease Gut Bacteria & Akkermansia muciniphila
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Cicer arietinum (Chickpea)
Effect of topical chickpea oil (Cicer arietinum L.) on knee osteoarthritis: A randomized double-blind controlled clinical trial
Abstract Introduction Chickpea oil (Cicer arietinum L.) is considered to have anti-inflammatory properties and is of therapeutic importance. It has been used topically in Persian medicine and compared other treatments and it is easily available and low cost. In clinical practice patients applying chickpea oil have expressed their satisfaction. Given the lack of valid scientific studies, this randomised controlled trial was conducted to evaluate the effect of topical chickpea oil on knees affected by osteoarthritis.... Analgesic, anti-inflammatory and diuretic activities of Cicer arietinum Linn https://www.researchgate.net/publication/322897652_Analgesic_anti-inflammatory_and_diuretic_activities_of_Cicer_arietinum_Linn |
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Rheumatoid arthritis is an systemic autoimmune disease
the pain most severe in the morning = stiffness RA usually effects the small joints of hands, feet, and wrists Immune system attacks the synovium (synovial membrane) that lines the joints Cause of RA is unknown but there is human leukocyte antigen (HLA) involvement Antibodies can connect to antigens and disable them. Antibodies can bind antigens together. Antibodies can connect to mast cells promoting the release of substances that cause inflammation. Vitamin D is great in the immune system it's an important regulator and communicator in the immune system These regulators are important for very specific cells called T cells and T cells are important in telling parts of the immune system how to work and how to function. |
Rheumatoid factor can be elevated in the serum in cases of Rheumatoid factor
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SLE
Tuberculosis
6 IMPORTANT risk factors associated with turbulence of blood flow that increase risk for IE
1. Congenital heart disease
2. Rheumatic heart disease
3. Mitral valve prolapse
4. Hypertrophic cardiomyopathy
5. Presence of a prosthetic valve
6. Previous endocarditis
FASCIA Oh it's painful I don't want to move.
Fascia provides agility, enough to prevent knocks and falls.
Arthritic changes ~ you're not guaranteed to lose all of the mobility, even after surgery, where surgeons cut through your fascia, but if you don't move, if your typical movement patterns don't involve moving to your end range, you will slowly lose that ability.
You can reverse some of that process if you start being more active and start moving through your full pain. Introducing full, free-range movement can support the growth and strengthen the fascia. A lot of what we consider to being tight or having shortened muscles is not really a true shortening. The central nervous system is responsible for regulating how much you were able to stretch or move. It's your tissues that are changing your perception how long your tissues are and now you evently you'll be able to move farther.
Tumors
Tumor is the non-specific, common term used to denote a neoplasm. Tumors are the classis signs of inflammation with lumps or swelling and they can be either classis or malignant. There are many types of tumors and hence they are named on bases of its origin. Treatment is also specific for each specific region. Related journals of Tumors Cancer, Tumor, Oncology and Cancer, Cancer Management and Research, Tumor Biology, , Cancer Biology & Research.
Epidemiology GeneticsGenetic epidemiology is the branch which deals with the role of genetic factors in determinant health and sickness in families and in populations, and therefore the interaction of such genetic factors with environmental factors.
Related journals of Epidemology Genetics
International journal of molecular epidemiology and Genetics(IJMG)
Translational medicineIt is a apace growing discipline in medicine analysis and aims to expedite the invention of recent diagnostic tools and treatments by employing a multi-disciplinary, extremely collaborative; "bench-to-bedside" approach.
Related Journals of Translational medicine
Journal of Translational Medicine, The Journal of Collaborative Healthcare and Translational Medicine (JCHTM),Journal of translational medicine and research,Journal of pathology and translational medicine, Journal of pathology and translational medicine
- Systemic lupus erythematosus (SLE) is the most common form of lupus — 70 % of people with lupus have it.
- is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels.
- Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus.
- Interstitial lung disease refers to a group of about 100 chronic lung disorders characterized by inflammation and scarring that make it hard for the lungs to get enough oxygen.
- Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver;
- Essential mixed cryoglobulinemia is characterized by joint pains and swelling (arthritis), enlargement of the spleen, skin vasculitis with purplish patches, and nerve and kidney disease. This can lead to recurrent pain in the abdomen, heart attack, and bleeding in the lungs.
Tuberculosis
- Tuberculosis is an infectious disease transmitted by Mycobacterium tuberculosis
- TB usually involves the lungs but also occurs in, kidneys, bones, lymph nodes, and meninges
- Hodgkin's lymphoma target Bcells
- Non hodgkins lymphoma targets B cell or T cells
- Risk factors for NH lymphoma , Pesticides, chemicals (DDT), Sporadic, Immune deficient patients, autoimmune disease
- increased age
6 IMPORTANT risk factors associated with turbulence of blood flow that increase risk for IE
1. Congenital heart disease
2. Rheumatic heart disease
3. Mitral valve prolapse
4. Hypertrophic cardiomyopathy
5. Presence of a prosthetic valve
6. Previous endocarditis
FASCIA Oh it's painful I don't want to move.
Fascia provides agility, enough to prevent knocks and falls.
Arthritic changes ~ you're not guaranteed to lose all of the mobility, even after surgery, where surgeons cut through your fascia, but if you don't move, if your typical movement patterns don't involve moving to your end range, you will slowly lose that ability.
You can reverse some of that process if you start being more active and start moving through your full pain. Introducing full, free-range movement can support the growth and strengthen the fascia. A lot of what we consider to being tight or having shortened muscles is not really a true shortening. The central nervous system is responsible for regulating how much you were able to stretch or move. It's your tissues that are changing your perception how long your tissues are and now you evently you'll be able to move farther.
Tumors
Tumor is the non-specific, common term used to denote a neoplasm. Tumors are the classis signs of inflammation with lumps or swelling and they can be either classis or malignant. There are many types of tumors and hence they are named on bases of its origin. Treatment is also specific for each specific region. Related journals of Tumors Cancer, Tumor, Oncology and Cancer, Cancer Management and Research, Tumor Biology, , Cancer Biology & Research.
Epidemiology GeneticsGenetic epidemiology is the branch which deals with the role of genetic factors in determinant health and sickness in families and in populations, and therefore the interaction of such genetic factors with environmental factors.
Related journals of Epidemology Genetics
International journal of molecular epidemiology and Genetics(IJMG)
Translational medicineIt is a apace growing discipline in medicine analysis and aims to expedite the invention of recent diagnostic tools and treatments by employing a multi-disciplinary, extremely collaborative; "bench-to-bedside" approach.
Related Journals of Translational medicine
Journal of Translational Medicine, The Journal of Collaborative Healthcare and Translational Medicine (JCHTM),Journal of translational medicine and research,Journal of pathology and translational medicine, Journal of pathology and translational medicine