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When you can't take pharmaceuticals
Adding essential minerals to combat irritable and violet humans Discovery Health Q96 Documentary www.youtube.com/watch?v=cNmHaV49row |
Ketamine for major depression: New tool, new questions
www.health.harvard.edu/blog/ketamine-for-major-depression-new-tool-new-questions-2019052216673
Once reserved for the party scene psychedelic drugs are making a comeback in an unlikely way as a promising treatment for depression and other mental illnesses. Magic mushrooms have been legal for some palliative patients in Canada for the past year. W5 investigation reveals another
psychedelic is also quietly being supported by the government for some Veterans struggling with depression and PTSD. W5: Harnessing the power of psychedelic drug therapy https://www.youtube.com/watch?v=sB9IhQXtBLg |
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Cannabis and the Heart April 18 2019 https://www.youtube.com/watch?v=QYCkVjdgDqQ
Some may experience the "Broken Heart Syndrome" which happens characteristically, in middle-aged women under terrible stress end up in the emergency part with what looks like a heart attack, from smoking marijuana.
Some may experience the "Broken Heart Syndrome" which happens characteristically, in middle-aged women under terrible stress end up in the emergency part with what looks like a heart attack, from smoking marijuana.
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CBD, like grapefruit, stops us peeing the drugs out. CBD is a very potent inhibitor CYP3A4 which is the same thing that grapefruits do, they block:
- calcium channel blocker -- statins an important pathway called 2d6 which metabolizes drugs that we take for:
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Emerging Paradigms in Mind–Body Medicine
Emerging Paradigms in Mind–Body Medicine
CHARLES SHANG, M.D. https://pdfs.semanticscholar.org/…/f3d25dd49088d862aee99896… Techniques involving the manipulation of the meridian system, such as acupuncture, yoga, and qigong, may activate the self-organizing system of an organism and improve it's structure and function at a more fundamental level than symptomatic relief. Development of these techniques may enable the diagnosis and treatment of a pathologic process at the early signal transduction stage, before the anatomic or morphologic change appears, and improve health beyond mere absence of disease. Acupuncture for chronic pain. Andrew J Vickers, Klaus Linde CLINICAL QUESTION Is acupuncture associated with reduced pain outcomes for patients with chronic pain compared with sham... Published 2014 in JAMA Cobalt Hell -- RT Documentary |
Best Homeopathic Medicines for Lipoma
Calcarea Carb: One theTop Homeopathic Medicines for Lipoma for Obese
Calcarea Carb is the one of the top constitutional Homeopathic medicines Lipoma. Generally the person requiring Calcarea Carb is obese. Various constitutional characters need to be verified before its use. The first among these is the tendency to sweat excessively on the head. The second is sensitivity to cold air. Last come the special demands in eating habits like a craving for boiled eggs and indigestible things like lime and chalk. Long-standing constipation and acidity may be found associated with Lipoma in a few cases. If these constitutional symptoms match the patient’s symptoms, Homeopathic medicine Calcarea Carb can help in complete disappearance of Lipomas.
Sulphur: Homeopathic medicine of great help in treatment of Lipomas
Sulphur is the next constitutional Homeopathic medicine that can prove extremely helpful in treating Lipomas. Sulphur is an equally powerful medicine like Calcarea Carb to treat Lipoma. But which medicine will suit which patient depends upon his or her constitution. Just like Calcarea Carb, Sulphur has unique constitutional symptoms for its use. An important constitutional feature for choosing Sulphur is extreme hot sensations in the body. The heat may be more marked in the palms, soles and head. The skin remains mostly dry and looks dirty. Some sort of skin trouble at present or in the past may be looked at while taking up the patient’s case. Another characteristic feature is a marked aversion to bathing. And In dietary habits, the patient may have a high demand for sweets.
Belladonna: One of the Top Grade Homeopathic medicines for painful Lipomas
Homeopathic medicine Belladonna is beneficial when the Lipoma is painful. The pain may worsen on touching the lump. Here, Belladonna will help in providing relief from pain and also dissolving the Lipoma.
Thuja: One of the Best Homeopathic Medicines for Lipomas
Thuja is a Homeopathic medicine that is of great help in treating abnormal growth originating anywhere in the body. Thuja possesses a powerful ability to help in complete dissipation of fatty accumulations. If a person with Lipomas has high blood cholesterol levels, the use of Homeopathic medicine Thuja is again very beneficial.
Calcarea Carb: One theTop Homeopathic Medicines for Lipoma for Obese
Calcarea Carb is the one of the top constitutional Homeopathic medicines Lipoma. Generally the person requiring Calcarea Carb is obese. Various constitutional characters need to be verified before its use. The first among these is the tendency to sweat excessively on the head. The second is sensitivity to cold air. Last come the special demands in eating habits like a craving for boiled eggs and indigestible things like lime and chalk. Long-standing constipation and acidity may be found associated with Lipoma in a few cases. If these constitutional symptoms match the patient’s symptoms, Homeopathic medicine Calcarea Carb can help in complete disappearance of Lipomas.
Sulphur: Homeopathic medicine of great help in treatment of Lipomas
Sulphur is the next constitutional Homeopathic medicine that can prove extremely helpful in treating Lipomas. Sulphur is an equally powerful medicine like Calcarea Carb to treat Lipoma. But which medicine will suit which patient depends upon his or her constitution. Just like Calcarea Carb, Sulphur has unique constitutional symptoms for its use. An important constitutional feature for choosing Sulphur is extreme hot sensations in the body. The heat may be more marked in the palms, soles and head. The skin remains mostly dry and looks dirty. Some sort of skin trouble at present or in the past may be looked at while taking up the patient’s case. Another characteristic feature is a marked aversion to bathing. And In dietary habits, the patient may have a high demand for sweets.
Belladonna: One of the Top Grade Homeopathic medicines for painful Lipomas
Homeopathic medicine Belladonna is beneficial when the Lipoma is painful. The pain may worsen on touching the lump. Here, Belladonna will help in providing relief from pain and also dissolving the Lipoma.
Thuja: One of the Best Homeopathic Medicines for Lipomas
Thuja is a Homeopathic medicine that is of great help in treating abnormal growth originating anywhere in the body. Thuja possesses a powerful ability to help in complete dissipation of fatty accumulations. If a person with Lipomas has high blood cholesterol levels, the use of Homeopathic medicine Thuja is again very beneficial.
Bergamot
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Bergamonte - HP Ingredients |
Bergamot Bitter Orange Powder
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Found most southern part of the Italian peninsula, Bergamot juice was traditionally recognized by the local population as a remedy for supporting
healthy cholesterol levels and cardiovascular health. The medicinal use of bergamot forgotten for decades is now being rediscovered burger montes health benefits are compelling it's used for:
Malathion is an Neil hesperidin - Matrix metallopeptidase 13 Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. It is a member of the matrix metalloproteinase family. Naringin rutten neo Desmond Roy Fallon and pond serum naringin has been shown to be beneficial in animal models of atherosclerosis while nearer citroen and rutin have been found to exhibit a strong capacity to prevent LDL from oxidation importantly bergamot juice is rich in bruge eridan and milton with an ability to inhibit hmg-coa reductase |
Historic Use:
Bergamot and bitter orange have been used as ingredients in herbal and flavored black teas and as a part of preparations for herbal remedies, and as a flavoring agent. The juice of bitter orange has been traditionally used in Africa as a topical antiseptic on ulcers and lesions (Morton, 1987). 1, 2, 3, 4 Table 1.0 ORAC5.0™ Comparative Results
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Facebook METHYLATION, downs syndrome
Down syndrome or Down's syndrome, also known as trisomy 21
Perhaps you have already heard of this girl on the cover of,
MD News Magazine - West Coast Edition Spring 2002 - Medical Update Glyconutrition and Nutraceuticals - The Next Phase of Dietary Supplements Michelle Desrochers, an American girl born with this so-called genetic defect, trisomy 21. And you can see her here, on the left photo, when she was 9 years old. On the right photo, we see her at the age of 14. What happened? Michelle Desrochers was born with a genetic defect, trisomy 21. She also had severe health problems regarding her immune system, concerning colon and lung, she was severely allergic, had severe asthmatic attacks, and repeatedly ended up on the emergency room due of asthmatic problems. Then, her parents learnt about a glyconutrient, and they simply started to give this to their child, and within days of ingestion, they saw that significant improvements came about. In this case, you can see the difference between 9 and 14 years. Her whole cognitive performance, her overall well-being improved so dramatically, Michelle could eventually attend high school and graduate. And, she was doing extremely well physically to the point that she could leave all those problems with her immune system behind her. This is really, you could say, a 'medical marvel'. Continue Reading: wlcollins.weebly.com/21st-century-medicine.htmlr |
EYE Health Cataracts
Many of us would not initially recognize cataracts as a major health issue, but for those living in developing countries this is not the case. At 51%, untreated cataracts are the leading cause of blindness in many poorer areas of the world. https://helpmesee.org/public-health-crisis-of-cataract-blindness/
Did Free Radicals Kill Lou Gehrig
- ALS can be both inherited or sporadic
- Theories behind the unknown etiology of ALS: multiple or cumulative mechanisms such as an autoimmune disorder or toxins
- What is the cardinal sign of ALS: muscle weakness (difficulty with fine motor skills, foot drop and falls, Bulbar, changes in their voice, difficulty with movement of tongue, and difficulty with opening and closing their mouth
Did Free Radicals Kill Lou Gehrig? Insights into the Complex Role of Peroxynitrite in Disease
https://www.youtube.com/watch?reload=9&v=yI05todLhmY |
A series of mutant human and yeast copper-zinc superoxide dismutases has been prepared, with mutations corresponding to those found in familial amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig9s disease). These proteins have been characterized with respect to their metal-binding characteristics and their redox reactivities. Replacement of Zn2+ ion in the zinc sites of several of these proteins with either Cu2+ or Co2+ gave metal-substituted derivatives with spectroscopic properties different from those of the analogous derivative of …https://www.pnas.org/content/pnas/93/22/12240.full.pdf ... these current studies have shown that the FALS mutations have dramatically altered both the metal binding and redox behavior of the human and yeast CuZnSOD. Further investigations are necessary to elucidate the link between the altered physical behavior and the disease itself. |
4-Aminobenzoic acid is an organic compound with the formula H2NC6H4CO2H. PABA, a white-grey crystalline substance, is only slightly soluble in water. It consists of a benzene ring substituted with an amino group and a carboxyl group. Video: 4-Aminobenzoic acid
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Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1218097/pdf/9020887.pdf
4-Aminobenzoic acid is an organic compound with the formula H₂NC₆H₄CO₂H. PABA is a white solid, although commercial samples can appear gray. It is slightly soluble in water. It consists of a benzene ring substituted with amino and carboxyl groups. The compound occurs extensively in the natural world. |
Kettle AJ, Gedye CA, Winterbourn CC (Jan 1997). "Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide". The Biochemical Journal. 321. 321 (2): 503–8. doi:10.1042/bj3210503. PMC 1218097. PMID 9020887.
Peroxynitrite-Scavenger
EPICATECHIN: Apple, Camellia sinensisTea leaves, Kratum ... (-)-EPIGALLOCATECHIN: Cotton stem (Gossypium sp), Bayleaf, ... https://phytochem.nal.usda.gov/phytochem/activities/show/1942?qlookup=Peroxynitrite&offset=0&max=20&et= Inhibitors of MPO
Azide has been used traditionally as an MPO inhibitor, but 4-aminobenzoic acid hydrazide (4-ABH) is a more specific inhibitor of MPO. Source: Myeloperoxidase - https://en.wikipedia.org/wiki/Myeloperoxidase#Inhibitors_of_MPO |
Jacob Jordaens. La familia del pintor 1622
Dietary Hyaluronic Acid -
Hyaluronic Acid - Benefits ALL skin type. What it does: molecules that can hold up to a thousand times it's weight in water so it offers immediate hydration.
**Uric acid is a waste product that can damage joints and tissue if it builds up too much in the body.
The Arachidonic acid Pathway
Cyclooxygenase is an enzyme that transforms arachidonic acid into endoperoxides which are used to synthesize prostaglandins, prostacyclin, or thromboxanes. Drugs such as aspirin and indomethacin inhibit cyclooxygenase and block the synthesis of prostaglandins and thromboxanes.
Thromboxane is a vasoconstrictor and a potent hypertensive agent, and it facilitates platelet aggregation.They act in the formation of blood clots and reduce blood flow to the site of a clot. https://en.wikipedia.org/wiki/Thromboxane Prostaglandins are powerful, locally-acting vasodilators and inhibit the aggregation of blood platelets. Through their role in vasodilation, prostaglandins are also involved in inflammation - image: https://en.wikipedia.org/wiki/Prostaglandin Cyclooxygenase enzymes: regulation and function F A Fitzpatrick https://pubmed.ncbi.nlm.nih.gov/14965321/ |
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Video:
Cyclooxygenase-1 and Cyclooxygenase-2 | Pharmacology https://www.youtube.com/watch?reload=9&v=vybF1ZACOyw
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Anti inflammatory Therapies, Part 6: Cyclooxygenase Inhibitors General Info
https://www.youtube.com/watch?v=c-OWqkUn5e4 |
Aspirin and Prostaglandin - Possible side effects of aspirin
https://www.youtube.com/watch?v=0YZ1vDzi_SM |
DHT dihydrotanshinone
The 12 Best Natural DHT Blockers
www.youtube.com/watch?v=FhijzrFOP0Q&feature=emb_logo12 Best Natural DHT Blockers (2020 Update) https://drformulas.com/blogs/news/best-natural-dht-blockers |
DHT molecules occur naturally inside the body. But as their production increases over time — tell-tale signs of aging, such as thinning hair, loose skin, and wrinkles, usually aren’t far behind. Theoretically, it meant that visible aging could be stopped by simply blocking the body’s production of DHT.
A DHT blood test from Walk-In Lab measures the amount of dihydrotestosterone (DHT) in the blood. DHT is best known for its roles in causing male pattern hair loss and prostate problems. The DHT blood test is also known as Dihydrotestosterone, Androstaner-3-one and Hydroxy-5α. How do I naturally balance DHT? Vegetables that contain zinc - spinach, kale, mushrooms, green peas, beet greens, sweet corn, etc. aid in blocking the production of DHT naturally. Also, including foods like watermelon, mangoes, tomatoes, carrots, etc., which contain lycopene in your diet controls the DHT levels in your body. Hair Loss: Myths and Realities | Carolyn Goh, MD - UCLA Health
https://www.youtube.com/watch?v=giBALq34cKs |
Why is the collagen in our skin so important? - MartiDerm |
https://phytochem.nal.usda.gov/phytochem/search/list dihydrotanshinone I toxicity
saw palmetto helps to thicken hair DHT is linked to hair loss helps skin stay firm and look younger as you age joints - amino acids, and dietar hydrolic acid to help joints but also helped with skin by producing new collegen hyaluronic acid (HA) -used as a mosturing skin care products - keeps joints lubricacted - drys up as we age - offered in supplements for wrinkles and dull skin collegen, saw palmetto, HA, VIT A& B supplements amblified with vitamins A and B Loose Sagging Skin |
Abstract
Recently, we have found for the first time that dihydrotanshinone I, isolated from Salvia miltiorrhiza, exhibited cytotoxicity against various tumor cell lines. To investigate whether the mechanism underlying dihydrotanshinone I toxicity involved apoptosis in cancer cell lines, we examined cell growth arrest and cell death by flow cytometric analysis and DNA fragmentation assay. Dihydrotanshinone I induced cell growth arrest during the S phase and subsequently, apoptosis, following its application to K562/ADR cells, whereas cryptotanshinone did not have these effects. These results suggest that the mode of action of dihydrotanshinone I involves apoptotic pathways that are different from those involved in cryptotanshinone toxicity. Biological activity of dihydrotanshinone I: Effect on apoptosis Dong-SunLee, Sang-HanLee https://www.sciencedirect.com/science/article/abs/pii/S1389172300888386 |
Healing Properties of ShungiteThe black rock is called Karelian Shungite. The mineral is found only in a specific part of Russia, named after a village called Shunga in Karelia, Russia.
It is said that these minerals are able to reduce the harmful effects of EMF waves and protect your home. The special properties of shungite are attributed to structures called fullerenes. The main feature of the fullerene is that the carbon atoms are arranged as connected pentagons and hexagons that form a sphere. Shungite shielded rats from the damaging effect of microwave radiations and has more unique beneficial properties described below: |
- Shungite samples were characterized by high absorbing capacity of microwave radiation. www.researchgate.net/publication/279183856_Mechanisms_of_Microwave_Absorption_in_Carbon_Compounds_from_Shungite
- Shungite shielded rats from the damaging effect of microwave radiations. This shows that shungite likely has positive shielding effect from electromagnetic radiations (http://shungite.com/rats.html).shungite.com/rats.html
- Shungite has an antioxidant and anti-inflammatory action against UVB-induced skin damage in hairless mice. www.hindawi.com/journals/omcl/2017/7340143/
- Shungite is able to both absorb and adsorb
- Shungite possesses s broad spectrum of of bactericidal properties; in a specific study the mineral was adsorptive active against some bacterial cells, phages, and E.coli. rspublication.com/ijst/dec13/2.pdf,
- With their high electronegativity, fullerenes appear in chemical reactions as strong oxidizing agents and remove free radicals out of water 30 times more effectively than activated carbon. rspublication.com/ijst/dec13/2.pdf
- Shungite adsorbs on its surface up to 95% of contaminant and is able to purify waste water from oil. rspublication.com/ijst/dec13/2.pdf
Aires Tech offers products to help reduce the effects of electromagnetic waves from common household devices. From the website: www.airestech.com/?ref=50
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Agency for Toxic Substances and Disease Registry Case Studies in Environmental Medicine (CSEM) Cadmium Toxicity Course:
https://www.atsdr.cdc.gov/csem/cadmium/docs/cadmium.pdf The patient’s problem list includes: back pain, glycosuria, proteinuria, severe osteomalacia and mild osteoporosis pseudo fractures, yellow discoloration of the teeth. All of these problems are consistent with chronic cadmium toxicity. The patient is also a smoker. Chronic cadmium exposure primarily affects the bones and kidneys and possibly the lungs. Renal dysfunction in this patient is indicated by the laboratory findings. The stooped posture, waddling gait, lumbar pain, and pain induced by spinal percussion are the result of skeletal changes and deformities. |
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This is extremely promising for the future of graphene based wearable electronics, which John says we should be on the lookout for in 2019. What we really hope is that we can walk into a room, five years from now, and most people in that room will have an article of clothing that has graphene wearable electronics in it. |
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Resources for chronic pain:
https://theacpa.org/Pain-Management-P... http://meetella.io/ http://facingfacialpain.org Resources for medical marijuana reform: http://norml.org/ |
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I was listening to dr. Joel Wallach the dead doctors don't lie doctor not too long ago and he was
telling a story about how Jerry Lewis brought the Muscular Dystrophy Association the cure for muscular dystrophy and they fired him oh and they didn't and they didn't put it out they don't want any cures they just want the research money cuz that that's correct there's no reason for any of these people the Heart Association the Cancer Association the Diabetes Association there's no reason for any of these people to want to cure because if there's a cure they're out of business I do not give a dime to cancer research because it's all wasted linus pauling once said most cancer research is a fraud and it's a jobs program to keep people employed and they just go round and round and round in circles and they keep announcing great breakthroughs and great discoveries and and which never pan out but they keep announcing new ones to keep you going they're really not doing anything that that will solve the problems and and they don't want to because you all these people will be unemployed and the bottom line is we already know how to cure camp so so you don't need to spend another dime on research because I already know how to do it so |
Currently we spend about 16% of our GMP on health care that's a huge number you think of that as for example in relationship to our defense spending
which is about six percent. |
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Vitamin and Mineral
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Deficiency
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A
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Preformed vitamin A, also called Retinol, is found in animal products and has multiple functions: maintain healthy immune function, normal vision, Cell growth, Gene transcription and protein formation, Skin health, etc.
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increased incidence and severity of infection, impaired vision, nausea and vomiting
headaches, bone pain and fractures, hair loss, liver damage, interference with vitamin K absorption |
B12 |
Vitamin B12 - refers to a family of Cobalamin containing cobalt in the centre. This family contains 6 analogs: - Adenosylcobalamin participates as a cofactor in radical-mediated 1,2-carbon skeleton rearrangements. Used for sluggish, viral liver - Methylcobalamin and Adenosylcobalamin
Taking vitamin B12 orally in combination with folic acid, and sometimes with vitamin B6, can reduce serum concentrations of homocysteine. Increased vitamin B12 during pregnancy, Thyrotoxicosis, Malignancy, liver and kidney disease. Insufficiencies are more common with older age and in persons eating a vegetarian or vegan diet as plants contain no B12. The most common cause of vitamin B12 deficiency is malabsorption due to inadequate IF production. - It Is called Pernicious anemia caused by: - 1 - Age related degeneration of gastric cells. - 2 - hereditary deficiencies in IF synthesis - 3- Autoimmune destruction of IF Availability and Absorption: 1 - vitamin is found in food bound to protein, its activity is retained during the cooking of most foods. 2 - Vit-B12 must be released from this protein by pepsin digestion in the stomach 3 - then combines with R-Protein and moves to duodenum 4 - It is the rebased from R-proetin and binds with Intrinsic factor. |
Deficiency can affect the entire body, leading to low energy, weight gain, and skin and thyroid problems, long-term diseases and neurological conditions.
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Copper
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Copper is an essential trace mineral present in all body tissues. This Mineral regulate various physiologic pathways, such as iron metabolism, connective tissue maturation, neurotransmission and energy production.
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anemia, seizures, nerve and bone abnormalities, reduced immune function
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D
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Vitamin D, the gut microbiome and inflammatory bowel disease. Seyed-Amir Tabatabaeizadeh, et al.,
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weak, deformed bones, poor growth (children) and loss of calcium in bones (adults), calcium deposits in soft tissues
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Iron
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Participates in a wide variety of highly complex metabolic processes including deoxyribonucleic acid (DNA) synthesis, and oxygen/electron transport.
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fatigue upon exertion, hair loss, poor immune function, anemia - small, pale red blood cells
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K
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Vitamin K is perhaps best known for its role in the blood clotting process. It is also absolutely essential to preventing heart disease and building strong bones. Women are usually low on vitamin K, supplement before surgery.
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raise the risk of excessive bleeding
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Potassium
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An adequate intake of potassium is important to maintain normal body growth, control the acid-base balance, build proteins, regulate digestive functioning, build muscle, and control the electrical activity of the heart.
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weakness, irritability, paralysis, irregular heartbeat, muscle cramps
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Magnesium
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Magnesium is an essential element for energy storage in the body’s cells. This mineral provides energy for almost all metabolic processes, being necessary for more than 300 chemical reactions in the human body.
Magnesium will clear drugs from your system faster as it speeds up the metabolic process and takes the pathogen out of your system. |
stunted growth in children, muscle weakness and pain, poor heart function
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Manganese
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Manganese mineral is important in the healthy bone structure metabolism and formation -helping to create essential enzymes for building bones- play a key role in the proper functioning of the thyroid gland.
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impaired growth, impaired reproductive function, skeletal abnormalities, impaired glucose tolerance, and altered carbohydrate and lipid metabolism
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phosphorus
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Next to calcium, phosphorus is the most abundant mineral in the body and an important role in activities for different body parts like the brain, kidney, heart and blood. Health benefits of phosphorous include cellular repair, protein formation, hormonal balance, improved digestion, proper nutrient utilization, and healthy bone formation.
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loss of appetite
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Selenium
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Selenium is an essential trace mineral that the body needs to stay healthy. Scientists and researchers suggests that Selenium prevent certain cancers such as stomach, colon, bladder, lung, skin, esophagus, and prostate.
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anemia, muscle pain and tnederness (keshan ad kashin), form of heart disease
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Sodium
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The optimal sodium intake allows the creation of electrolytes and an essential ion present in the extracellular fluid (ECF). However, high levels of sodium in the body are associated with high blood pressure and hypertension.
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weakness, apathy, poor appetite, muscle cramps
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Thiamin
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Thiamin - nerve disorders, mental confusion, heart irregularity and failure
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nerve disorders, mental confusion, heart irregularity and failure
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Zinc
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Zinc is an really vital mineral for the human body as it helps in regulation of the cells production in the immune system. The health benefits of Zinc include reduction of stress levels, control of diabetes, digestion, proper functioning of immune system, and energy metabolism.Zinc is an really vital mineral for the human body as it helps in regulation of the cells production in the immune system. The health benefits of Zinc include reduction of stress levels, control of diabetes, digestion, proper functioning of immune system, and energy metabolism.
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growth failure, slow wound healing, skin rash, diarrhea, depressed sense of taste and smell
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Biotin - hair loss (alopecia) and a scaly red rash around the eyes, nose, mouth, and genital area. Neurologic symptoms in adults have included depression, lethargy, hallucinations, numbness and tingling of the extremities, ataxia, and seizures
Calcium - This vital mineral is best known to strengthen bones, teeth, the heart, and slash your risk of developing a number of diseases like hypertension or seizures. Deficiency results in poorly mineralized bones, increased risk of osteoporosis and hypertension
Chloride (Cl⁻) - muscle cramps, poor diet, long-term mental retardation in infants, convulsions (observed in infants)
Choline - fatty liver, infertility
Chromium - elevated blood glucose and triglyceride levels after meals. It is an essential micronutrient in animal physiology, playing a role in glucose and lipid metabolism (Anderson, 1989; Mertz, 1993). It is involved in peripheral action of insulin, normal glucose utilization, and stimulation of enzyme systems (Mertz, 1969), and possibly in the stabilization of nucleic acids (Huff et al., 1964). Read More:
Cobalt - is a central component of Vitamin B12. Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is involved in the metabolism of every cell of the human body: it is a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism.[1] It is particularly important in the normal functioning of the nervous system via its role in the synthesis of myelin,[2][3] and in the maturation of developing red blood cells in the bone marrow.[4] B12 from consuming animal products including meat, milk, eggs, and fish.[6] Vitamin B12 is rare from plant sources, so vegetarians are more likely to suffer from vitamin B12 deficiency. Infants are at a higher risk of vitamin B12 deficiency if they were born to vegetarian mothers
Fluoride - no true deficiency
Folate - increased risk for neural tube defects, megaloblastic cells (may stimulate cancer growth) and anemia
Iodine - goiter and cretinism (intellectual impairment and poor growth in infants of women who were iodine deficient during pregnancy)
Molybdenum - rapid heartbeat and breathing (coma), characterized by severe neurologic abnormalities in affected patients, Wilson's disease (a genetic disease), Variation in esophageal cancer incidence worldwide has been linked to the molybdenum content in soils and food.
Niacin - skin disorders, diarrhea and indigestion, (nicotinamide, nicotinic acid) flushing of facial skin, itchy skin, nausea and vomiting, liver damage
Pantothenic acid - fatigue, sleep disturbances, numbness, impaired coordination
Riboflavin - reddened lips, cracks at both corners of mouth
Vitamin B12 - neurological disorders, pernicious anemia characterized by large, oval-shaped red blood cells
Vitamin B6 - irritability, depression, convulsions, twitching, muscular weakness, (pyridoxine)
nerve destruction (kidney stones)
Vitamin C - bleeding and bruising easily due to weakened blood vessels, cartilage and other tissues containing collagen, diarrhea GI tract discomfort
Vitamin E - muscle loss, anemia, weakness, excessive bleeding as a result of interfering with vitamin K metabolism
Vitamin K - bleeding, bruises
VDR receptors
Vitamin D3
Microbial overgrowth and increased inflammation from gut issues can change the body’s need for vitamin D. In someone that is having chronic infections; it is not odd to see their blood test results show that they have high 1-25 hydroxy and low 25-hydroxy. Elevated 1-25 hydroxy is one way the body tries to fight the overgrowth through chronic immune activation and to activate VDR receptors to enhance the immune system. Their VDR receptors become changed epigenetically, possibly from your chronic infections or environment. 1-25 vitamin D increases CD14 gene expression, which helps the immune system recognize endotoxins and eliminate them. The less active your VDR receptors are in the gut, the more vulnerable you are to endotoxins and leaky gut. “Autoimmune” conditions that improve once vitamin D is normalized in the body and gut health is restored include: •Rheumatoid arthritis, Alzheimer’s, Diabetes (type 1 and 2), IBD, Multiple Sclerosis, Parkinson’s disease, Psoriasis, Systemic lupus erythematosus
Always make sure the vitamin D in the supplement is D3 and not the inferior D2. It is always best to get your vitamin D from proper sunlight exposure instead of supplements.
The best way to help correct this imbalance is to Fix Your Gut, reduce the chronic infection, fix your circadian rhythm, reduce Th1 / Th2 dominance, and maintain
proper sunlight exposure. Over time, the VDR receptors should change epigenetically and facilitate proper vitamin D metabolism, returning your markers
to normal. Proper sunlight exposure is something that most people can do for free to improve their overall health. Not enough people in today’s modern world get enough sunlight, and most people are vitamin D deficient. Endogenous vitamin D is very important for proper health and can be obtained easily from the sun in most cases. Recommended Supplement of Vitamin D3: Jarrow Formulas Vitamin D3 5000IU
Vitamin E
Vitamin E toxicity is rare , but nonetheless, hypervitaminosis E is still very
possible. Toxicity symptoms have been noted at doses greater than 1,500 IU daily. I do not usually recommend vitamin E supplementation outside of what is found
in a multivitamin. Most people get adequate amounts of vitamin E in their diet, and deficiency is rare. Vitamin E supplementation might help with heart disease and people
suffering from diabetes by lowering overall oxidative stress. Avoid vitamin E that is synthetically made (dl) and try to use a supplement that is non
-GMO and has mixed tocopherols.If you need to supplement with vitamin E, take 400 IU daily at the most, but you can take up to 1,000 IU daily in divided doses if needed. Also
, discontinue all vitamin E supplementation at least a month before elective surgery and notify your doctor if you are taking vitamin E because it can be considered a blood thinner.Hypervitaminosis E Symptoms: Vitamin E,KPossible Impaired Blood Clotting, Possible Hemorrhage,
Vitamin K
Deficiency, Blotchy Skin, Increased Triglycerides.Hypervitaminosis K only applies to people who are using blood-thinningmedications like Warfarin that inhibits vitamin K in the human body. Vitamin K has no upper tolerable limit in the body, and there are no known toxicity issues with any natural vitamin K1 / vitamin K2 supplement. Vitamin K3 (menadione) on the other hand which is synthetic vitamin K, interfered with the function glutathione and is known to cause liver failure with its use. It is banned in the United States.If you are taking vitamin K inhibitors, talk to your doctor about supplement low doses vitamin K supplements so that a proper balance between the medication and vitamin K can be achieved
. Important information about this can be found here: http://www.lef.org/magazine/mag2007/jun2007_report_vitamink_01.htm Recommended Supplement of Vitamin K: Life Extension Super K SupplementChapter 7 Hypermineralosis and SupplementsHypermineralosis rarely occurs if one is cautious of their mineral supplementation
amounts and daily dietary intake of minerals. Hypermineralosis can occur though in people taking multiple supplements daily without proper knowledge. Some minerals more than others should be supplemented using caution. All minerals
have daily upper tolerable intake limits, and I will list them separately from the individual minerals that are in this chapter that require more caution with supplementation. Remember, upper tolerable intake limits are the highest dose that one can take daily without developing hypermineralosis in most cases, but this dose
is not the true therapeutic dose of the mineral for most people and should only be used under doctor’s supervision. Mineral Daily Upper Tolerable Intake Limits
Boron – Twenty mg dailyChromium – 1,000 mcg (Chromium Picolinate at this dosage has been linked
to kidney damage in a few reported instances)Iodine – Fifty mg daily under medical supervision, if not under medical supervision ten mg daily
Molybdenum–Two mg dailyNickel: – One mg daily (do not recommend supplementation due to allergies associated with its use)Phosphorus: – Four grams daily (including dietary intake) Potassium: – 1,000 mg daily from supplementation, 10,000 mg dietary + supplementation maximum daily intakeSodium - Ten grams daily
Vanadium - – Two mg dailyCalcium Upper Tolerable Limit (Supplementation + Dietary) – 2,500 mg daily Recommended Daily Supplementation Limit – 1,000 mgHypercalcemia rarely occurs because of diet alone. It is possible for people with kidney issues, hyperparathyroidism, malignant tumors, lithium use, hypervitaminosis A , or if you are suffering from hypervitaminosis D to suffer from hypercalcemia from dietary sources. Most people develop hypercalcemia from taking in too much calcium from supplements and dietary choices. You also have to be careful when using the antacid calcium carbonate in large dose
s (doses outside recommended therapeutic range on the drug notes, also known as milk-alkali syndrome) which can easily cause hypercalcemia. Symptoms of mild/moderate hypercalcemia include loss of appetite, nausea, vomiting, constipation, abdominal cramps, dry mouth, thirst, bone pain, depression, kidney stones, and frequent urination. Abnormal heart rhythm and calcification of arteries can also occur. Mild to moderate symptoms of hypercalcemia are common if your total calcium blood level is around 12 mg/dl.Symptoms of severe hypercalcemia, on the other hand, is very serious and include confusion, delirium, and coma . Severe symptoms of hypercalcemia are common if your total calcium blood level is above 15 mg/dl.Hypercalcemia is usually treated by increased hydration to eliminate
calcium;diuretic may also be needed for greater kidney clearance of calcium. Bisphosphonates and calcitonin may also be given to prevent bone reabsorption of
calcium.Calcium is not needed to be supplemented by most people because enough is usually obtained
through the diet. Some women with osteoporosis may choose to supplement with calcium to increase bone strength. Remember to supplement with magnesium if you
choose to take a calcium supplement. Supplementation of magnesium helps the body eliminate excess calcium, and maintain mineral homeostasis.
Remember if you do supplement with calcium, supplement with the superior citrate form and no more than 500 mg every twelve hours for maximum
absorption.CopperUpper Tolerable Limit (Supplementation + Dietary)– 10 mg daily Recommended Daily Supplementation Limit – 2 mg
Like most instances of hypermineralosis, copper toxicity rarely occurs from dietary sources alone.Copper toxicity in the general population occurs from eating toxic amounts of leached copper from uncoated copper cookware, ingestion of excess copper in drinking water, occupational exposure to excess copper, excessive amounts of copper from supplementation, and can occur if you have Wilson’s disease.Wilson’s disease is an inherited genetic disorder in which excess copper accumulates in tissues due to a mutation in the ATP7B gene.
This disease if left untreated will eventually lead to liver failure. People with Wilson’s disease should avoid copper cookware, copper-containing supplements, and food that is high in dietary copper.
Symptoms of mild/moderate copper toxicity include loss of appetite, nausea, vomiting, melena, jaundice, abdominal cramps, low zinc serum levels, and diarrhea.
Symptoms of severe copper toxicity include severe liver and kidney failure, jaundice, and coma.The heavy metal chelation agent’s penicillamine and dimercaprol are used to
remove excess copper from the body but can be quite harsh chelating agents. Excessive copper intake, more than two mg daily, can upset the zinc to copper ratio in the body and can create a zinc deficiency.
If you take two mg of copper daily for a few months, fifteen mg of zinc supplementation daily might also be needed to help stop the possibility of developing a zinc deficiency.
One study also mentioned that supplementation of copper at eight mg daily for long term instances might lower the immune systemwhile another study showed that supplementation of long-term copper at that dosage causes no such medical issue. Excessive copper buildup and toxicity
can make adrenal fatigue symptoms worse, so limit copper
intake during zinc supplementation until adrenals have healed. Unbounded copper ingestion from supplements may cause issues with copper overload and problems with inhibiting ceruloplasmin. For most people ingestion of liver once or twice a
week should be sufficient for ceruloplasmin bonded copper.The recommended form of copper for supplementation is copper glycinate.
IronUpper Tolerable Limit Supplementation in Men That Are Not Anemic – zero mgUpper Tolerable Limit Supplementation in Men / Women That Require Iron Supplementation
– 45 mgIron overload is of most concern out of any of the hypermineralosis conditions. If you suffer from hemochromatosis or have the medical conditions sideroblastic
anemia, pyruvate kinase deficiency, or thalassemia major, dietary iron intake and supplementation need to be monitored by a doctor because iron overload is a real
possibility. If you are a non-anemic male, iron supplementation should also be monitored by a doctor as well. Iron supplementation should be monitored
in children as well; accidental iron overload/poisoning is the number one cause of poisoning fatalities in children under six years of age. Menstruating women
/ pregnant women might require iron supplementation, but unless indicated by the doctor no more than 45 mg should be taken daily.Most people get enough iron in their diet and supplementation is not needed.
Vegans might have to supplement with iron because plant-based iron is not very bioavailable.Symptoms of acute iron overload/toxicity include
nausea, vomiting, abdominal pain, tarry stools, lethrgy, weak and rapid pulse, low blood pressure, and fever. If poisoning dosages are large enough, organ failure and coma can occur.Symptoms of long-
term iron overload (seen in conditions like hemochromatosis) include cirrhosis of the liver, diabetes, cardiomyopathy, arthritis, testicular failure, tanning of the skin, and joint/bone pain.
Diagnosis of iron overload can be made from a serum ferritin blood test. Diagnosis of systemic iron deposits and damage occurred in the body can be seen by
performing a liver biopsy and an MRI. Genetic testing for hemochromatosis can be done by testing the HFE (human hemochromatosis protein) gene.Treatments for iron overload include bloodletting and chelating agents like
deferoxamine.I do not recommend the supplementation or iron it inhibits ceruloplasmin and may feed gut overgrowth.If you need to supplement with iron the best form of iron to use is iron
bisglycinate. Most forms of iron tend to cause gastrointestinal upset and constipation, iron bisglycinate seems to be the best-absorbed
form, and least likely to cause those issues.
Manganese
Upper Tolerable Limit (Supplementation + Dietary)– 11 mg daily Recommended Daily Supplementation Limit– 1 mg
Manganese hypermineralosis is a real threat with most of the multivitamin supplements on the market today. Manganese deficiency in the diet is extremely
rare; most people get more than the two mg daily they need for optimal functioning. In addition, if you drink well or even tap water, manganese
is concentrated in most water sources and can add to your total daily intake of the mineral.Manganese is important for the body though it is used in the production of
manganese superoxide dismutase a principal mitochondrial antioxidant. Manganese is important for proper metabolism, bone development, and wound healing.
Manganese in large doses though is a neurotoxin. Manganese poisoning causes many neurologic and physical problems that resemble diseases including Parkinson’s disease and schizophrenia. A study from Greece concluded
that people who ingested water with natural manganese levels as low as 2.3 mg a liter would show neurological symptoms. Another study showed that children who ingested rich natural manganese water experienced cognitive and behavioral deficits. The
EPA even limits manganese concentrations in drinking water to 0.05 mg/ liter. Toxicity from inhaling manganese dust (known as manganism) can be an occupational hazard, and cause a more rapid onset of neurological symptoms
including tremors, irritability, aggressiveness, hallucinations difficulty walking , and facial muscle spasms.My recommended daily supplementation limit of manganese is one mg, and I caution that no more than two mg be supplemented
daily.Magnesium Upper Tolerable Limit Supplementation – 600mg per fifty pounds of body weight dailyHypermagnesemia is a rare
condition in which a person has too much magnesiumin their blood plasma. Hypermagnesemia usually does not occur in people that takesupplemental magnesium,
but it can occur if a person has impaired kidneyfunction. IV magnesium bypasses the body’s digestion entropy and has a greaterchance of
leading to overdose. In vivo, the body has many mechanisms in place to prevent an overdose from supplemental magnesium.
Diagnostic symptoms are usually a combination of lowblood sugar and highcalcium. Symptoms usually include weakness, vomiting, impaired breathing,hypotension, increased blood calcium levels, arrhythmia, lack of muscle reflexes,and bradycardia(slow heart rate). It is possible that if one's plasma magnesiumlevel is too high, the heart could stop, causing a "heart attack." This is because magnesium is a muscle relaxant, but this outcome is extremely rare.Treatment for hypermagnesemia includes giving IV calcium gluconate to inactivate free magnesium through a binding process. The calcium also reactivatesthe muscle cells because calcium is a muscle stimulator. Finally, dialysis might be needed in some cases to eliminate excess magnesium, and to help with kidney function.
Selenium
Upper Tolerable Limit (Supplementation + Dietary) – 400 mcg dailyRecommended Daily Supplementation Limit– 400 mcg dailyProper selenium intake is very important for overall health. Selenium is important for glutathione peroxidase production, proper production of thyroid hormones, iodine absorption, many different selenoproteins production, and proper testosterone function.Selenosis is a common hypermineralosis condition where the body contains
excessive amounts of selenium. Selenosis has been reported from both the supplementation of selenium and dietary sources. Selenosis can stem from ingesting fruits and vegetables grown in soil high in selenium, ingesting water that is high in selenium mineral content, and overeating selenium rich foods including Brazil nuts.Brazil nuts are very high in selenium, and even one ounce of Brazil nuts can contain 544 mcg of selenium that is well over your upper tolerable daily limit. Selenium toxicity has also been reported in thirteen individuals after taking supplements that contained large amounts of selenium during a manufacturing error. Because of the real risk of selenosis, selenium should not be supplemented over 400 mcg daily, unless monitored by a doctor.Symptoms of mild/moderate selenosis include nail brittleness, hair loss, gastrointestinal disturbances, skin rashes, garlic breath odor, fatigue, irritability, and nervous system issues.
Vitamin D3
Microbial overgrowth and increased inflammation from gut issues can change the body’s need for vitamin D. In someone that is having chronic infections; it is not odd to see their blood test results show that they have high 1-25 hydroxy and low 25-hydroxy. Elevated 1-25 hydroxy is one way the body tries to fight the overgrowth through chronic immune activation and to activate VDR receptors to enhance the immune system. Their VDR receptors become changed epigenetically, possibly from your chronic infections or environment. 1-25 vitamin D increases CD14 gene expression, which helps the immune system recognize endotoxins and eliminate them. The less active your VDR receptors are in the gut, the more vulnerable you are to endotoxins and leaky gut. “Autoimmune” conditions that improve once vitamin D is normalized in the body and gut health is restored include: •Rheumatoid arthritis, Alzheimer’s, Diabetes (type 1 and 2), IBD, Multiple Sclerosis, Parkinson’s disease, Psoriasis, Systemic lupus erythematosus
Always make sure the vitamin D in the supplement is D3 and not the inferior D2. It is always best to get your vitamin D from proper sunlight exposure instead of supplements.
The best way to help correct this imbalance is to Fix Your Gut, reduce the chronic infection, fix your circadian rhythm, reduce Th1 / Th2 dominance, and maintain
proper sunlight exposure. Over time, the VDR receptors should change epigenetically and facilitate proper vitamin D metabolism, returning your markers
to normal. Proper sunlight exposure is something that most people can do for free to improve their overall health. Not enough people in today’s modern world get enough sunlight, and most people are vitamin D deficient. Endogenous vitamin D is very important for proper health and can be obtained easily from the sun in most cases. Recommended Supplement of Vitamin D3: Jarrow Formulas Vitamin D3 5000IU
Vitamin E
Vitamin E toxicity is rare , but nonetheless, hypervitaminosis E is still very
possible. Toxicity symptoms have been noted at doses greater than 1,500 IU daily. I do not usually recommend vitamin E supplementation outside of what is found
in a multivitamin. Most people get adequate amounts of vitamin E in their diet, and deficiency is rare. Vitamin E supplementation might help with heart disease and people
suffering from diabetes by lowering overall oxidative stress. Avoid vitamin E that is synthetically made (dl) and try to use a supplement that is non
-GMO and has mixed tocopherols.If you need to supplement with vitamin E, take 400 IU daily at the most, but you can take up to 1,000 IU daily in divided doses if needed. Also
, discontinue all vitamin E supplementation at least a month before elective surgery and notify your doctor if you are taking vitamin E because it can be considered a blood thinner.Hypervitaminosis E Symptoms: Vitamin E,KPossible Impaired Blood Clotting, Possible Hemorrhage,
Vitamin K
Deficiency, Blotchy Skin, Increased Triglycerides.Hypervitaminosis K only applies to people who are using blood-thinningmedications like Warfarin that inhibits vitamin K in the human body. Vitamin K has no upper tolerable limit in the body, and there are no known toxicity issues with any natural vitamin K1 / vitamin K2 supplement. Vitamin K3 (menadione) on the other hand which is synthetic vitamin K, interfered with the function glutathione and is known to cause liver failure with its use. It is banned in the United States.If you are taking vitamin K inhibitors, talk to your doctor about supplement low doses vitamin K supplements so that a proper balance between the medication and vitamin K can be achieved
. Important information about this can be found here: http://www.lef.org/magazine/mag2007/jun2007_report_vitamink_01.htm Recommended Supplement of Vitamin K: Life Extension Super K SupplementChapter 7 Hypermineralosis and SupplementsHypermineralosis rarely occurs if one is cautious of their mineral supplementation
amounts and daily dietary intake of minerals. Hypermineralosis can occur though in people taking multiple supplements daily without proper knowledge. Some minerals more than others should be supplemented using caution. All minerals
have daily upper tolerable intake limits, and I will list them separately from the individual minerals that are in this chapter that require more caution with supplementation. Remember, upper tolerable intake limits are the highest dose that one can take daily without developing hypermineralosis in most cases, but this dose
is not the true therapeutic dose of the mineral for most people and should only be used under doctor’s supervision. Mineral Daily Upper Tolerable Intake Limits
Boron – Twenty mg dailyChromium – 1,000 mcg (Chromium Picolinate at this dosage has been linked
to kidney damage in a few reported instances)Iodine – Fifty mg daily under medical supervision, if not under medical supervision ten mg daily
Molybdenum–Two mg dailyNickel: – One mg daily (do not recommend supplementation due to allergies associated with its use)Phosphorus: – Four grams daily (including dietary intake) Potassium: – 1,000 mg daily from supplementation, 10,000 mg dietary + supplementation maximum daily intakeSodium - Ten grams daily
Vanadium - – Two mg dailyCalcium Upper Tolerable Limit (Supplementation + Dietary) – 2,500 mg daily Recommended Daily Supplementation Limit – 1,000 mgHypercalcemia rarely occurs because of diet alone. It is possible for people with kidney issues, hyperparathyroidism, malignant tumors, lithium use, hypervitaminosis A , or if you are suffering from hypervitaminosis D to suffer from hypercalcemia from dietary sources. Most people develop hypercalcemia from taking in too much calcium from supplements and dietary choices. You also have to be careful when using the antacid calcium carbonate in large dose
s (doses outside recommended therapeutic range on the drug notes, also known as milk-alkali syndrome) which can easily cause hypercalcemia. Symptoms of mild/moderate hypercalcemia include loss of appetite, nausea, vomiting, constipation, abdominal cramps, dry mouth, thirst, bone pain, depression, kidney stones, and frequent urination. Abnormal heart rhythm and calcification of arteries can also occur. Mild to moderate symptoms of hypercalcemia are common if your total calcium blood level is around 12 mg/dl.Symptoms of severe hypercalcemia, on the other hand, is very serious and include confusion, delirium, and coma . Severe symptoms of hypercalcemia are common if your total calcium blood level is above 15 mg/dl.Hypercalcemia is usually treated by increased hydration to eliminate
calcium;diuretic may also be needed for greater kidney clearance of calcium. Bisphosphonates and calcitonin may also be given to prevent bone reabsorption of
calcium.Calcium is not needed to be supplemented by most people because enough is usually obtained
through the diet. Some women with osteoporosis may choose to supplement with calcium to increase bone strength. Remember to supplement with magnesium if you
choose to take a calcium supplement. Supplementation of magnesium helps the body eliminate excess calcium, and maintain mineral homeostasis.
Remember if you do supplement with calcium, supplement with the superior citrate form and no more than 500 mg every twelve hours for maximum
absorption.CopperUpper Tolerable Limit (Supplementation + Dietary)– 10 mg daily Recommended Daily Supplementation Limit – 2 mg
Like most instances of hypermineralosis, copper toxicity rarely occurs from dietary sources alone.Copper toxicity in the general population occurs from eating toxic amounts of leached copper from uncoated copper cookware, ingestion of excess copper in drinking water, occupational exposure to excess copper, excessive amounts of copper from supplementation, and can occur if you have Wilson’s disease.Wilson’s disease is an inherited genetic disorder in which excess copper accumulates in tissues due to a mutation in the ATP7B gene.
This disease if left untreated will eventually lead to liver failure. People with Wilson’s disease should avoid copper cookware, copper-containing supplements, and food that is high in dietary copper.
Symptoms of mild/moderate copper toxicity include loss of appetite, nausea, vomiting, melena, jaundice, abdominal cramps, low zinc serum levels, and diarrhea.
Symptoms of severe copper toxicity include severe liver and kidney failure, jaundice, and coma.The heavy metal chelation agent’s penicillamine and dimercaprol are used to
remove excess copper from the body but can be quite harsh chelating agents. Excessive copper intake, more than two mg daily, can upset the zinc to copper ratio in the body and can create a zinc deficiency.
If you take two mg of copper daily for a few months, fifteen mg of zinc supplementation daily might also be needed to help stop the possibility of developing a zinc deficiency.
One study also mentioned that supplementation of copper at eight mg daily for long term instances might lower the immune systemwhile another study showed that supplementation of long-term copper at that dosage causes no such medical issue. Excessive copper buildup and toxicity
can make adrenal fatigue symptoms worse, so limit copper
intake during zinc supplementation until adrenals have healed. Unbounded copper ingestion from supplements may cause issues with copper overload and problems with inhibiting ceruloplasmin. For most people ingestion of liver once or twice a
week should be sufficient for ceruloplasmin bonded copper.The recommended form of copper for supplementation is copper glycinate.
IronUpper Tolerable Limit Supplementation in Men That Are Not Anemic – zero mgUpper Tolerable Limit Supplementation in Men / Women That Require Iron Supplementation
– 45 mgIron overload is of most concern out of any of the hypermineralosis conditions. If you suffer from hemochromatosis or have the medical conditions sideroblastic
anemia, pyruvate kinase deficiency, or thalassemia major, dietary iron intake and supplementation need to be monitored by a doctor because iron overload is a real
possibility. If you are a non-anemic male, iron supplementation should also be monitored by a doctor as well. Iron supplementation should be monitored
in children as well; accidental iron overload/poisoning is the number one cause of poisoning fatalities in children under six years of age. Menstruating women
/ pregnant women might require iron supplementation, but unless indicated by the doctor no more than 45 mg should be taken daily.Most people get enough iron in their diet and supplementation is not needed.
Vegans might have to supplement with iron because plant-based iron is not very bioavailable.Symptoms of acute iron overload/toxicity include
nausea, vomiting, abdominal pain, tarry stools, lethrgy, weak and rapid pulse, low blood pressure, and fever. If poisoning dosages are large enough, organ failure and coma can occur.Symptoms of long-
term iron overload (seen in conditions like hemochromatosis) include cirrhosis of the liver, diabetes, cardiomyopathy, arthritis, testicular failure, tanning of the skin, and joint/bone pain.
Diagnosis of iron overload can be made from a serum ferritin blood test. Diagnosis of systemic iron deposits and damage occurred in the body can be seen by
performing a liver biopsy and an MRI. Genetic testing for hemochromatosis can be done by testing the HFE (human hemochromatosis protein) gene.Treatments for iron overload include bloodletting and chelating agents like
deferoxamine.I do not recommend the supplementation or iron it inhibits ceruloplasmin and may feed gut overgrowth.If you need to supplement with iron the best form of iron to use is iron
bisglycinate. Most forms of iron tend to cause gastrointestinal upset and constipation, iron bisglycinate seems to be the best-absorbed
form, and least likely to cause those issues.
Manganese
Upper Tolerable Limit (Supplementation + Dietary)– 11 mg daily Recommended Daily Supplementation Limit– 1 mg
Manganese hypermineralosis is a real threat with most of the multivitamin supplements on the market today. Manganese deficiency in the diet is extremely
rare; most people get more than the two mg daily they need for optimal functioning. In addition, if you drink well or even tap water, manganese
is concentrated in most water sources and can add to your total daily intake of the mineral.Manganese is important for the body though it is used in the production of
manganese superoxide dismutase a principal mitochondrial antioxidant. Manganese is important for proper metabolism, bone development, and wound healing.
Manganese in large doses though is a neurotoxin. Manganese poisoning causes many neurologic and physical problems that resemble diseases including Parkinson’s disease and schizophrenia. A study from Greece concluded
that people who ingested water with natural manganese levels as low as 2.3 mg a liter would show neurological symptoms. Another study showed that children who ingested rich natural manganese water experienced cognitive and behavioral deficits. The
EPA even limits manganese concentrations in drinking water to 0.05 mg/ liter. Toxicity from inhaling manganese dust (known as manganism) can be an occupational hazard, and cause a more rapid onset of neurological symptoms
including tremors, irritability, aggressiveness, hallucinations difficulty walking , and facial muscle spasms.My recommended daily supplementation limit of manganese is one mg, and I caution that no more than two mg be supplemented
daily.Magnesium Upper Tolerable Limit Supplementation – 600mg per fifty pounds of body weight dailyHypermagnesemia is a rare
condition in which a person has too much magnesiumin their blood plasma. Hypermagnesemia usually does not occur in people that takesupplemental magnesium,
but it can occur if a person has impaired kidneyfunction. IV magnesium bypasses the body’s digestion entropy and has a greaterchance of
leading to overdose. In vivo, the body has many mechanisms in place to prevent an overdose from supplemental magnesium.
Diagnostic symptoms are usually a combination of lowblood sugar and highcalcium. Symptoms usually include weakness, vomiting, impaired breathing,hypotension, increased blood calcium levels, arrhythmia, lack of muscle reflexes,and bradycardia(slow heart rate). It is possible that if one's plasma magnesiumlevel is too high, the heart could stop, causing a "heart attack." This is because magnesium is a muscle relaxant, but this outcome is extremely rare.Treatment for hypermagnesemia includes giving IV calcium gluconate to inactivate free magnesium through a binding process. The calcium also reactivatesthe muscle cells because calcium is a muscle stimulator. Finally, dialysis might be needed in some cases to eliminate excess magnesium, and to help with kidney function.
Selenium
Upper Tolerable Limit (Supplementation + Dietary) – 400 mcg dailyRecommended Daily Supplementation Limit– 400 mcg dailyProper selenium intake is very important for overall health. Selenium is important for glutathione peroxidase production, proper production of thyroid hormones, iodine absorption, many different selenoproteins production, and proper testosterone function.Selenosis is a common hypermineralosis condition where the body contains
excessive amounts of selenium. Selenosis has been reported from both the supplementation of selenium and dietary sources. Selenosis can stem from ingesting fruits and vegetables grown in soil high in selenium, ingesting water that is high in selenium mineral content, and overeating selenium rich foods including Brazil nuts.Brazil nuts are very high in selenium, and even one ounce of Brazil nuts can contain 544 mcg of selenium that is well over your upper tolerable daily limit. Selenium toxicity has also been reported in thirteen individuals after taking supplements that contained large amounts of selenium during a manufacturing error. Because of the real risk of selenosis, selenium should not be supplemented over 400 mcg daily, unless monitored by a doctor.Symptoms of mild/moderate selenosis include nail brittleness, hair loss, gastrointestinal disturbances, skin rashes, garlic breath odor, fatigue, irritability, and nervous system issues.
What are Endangered Elements:Of the 118 elements that make up everything—from the compounds in a chemist’s arsenal to consumer products on the shelf—44 will face supply limitations in the coming years. These critical elements include rare earth elements, precious metals, and even some that are essential to life, like phosphorus.
www.acs.org/content/acs/en/greenchemistry/research-innovation/endangered-elements.html A list of 14 geochemically scarce metals: antimony, beryllium, chromium, cobalt, gallium, germanium, gold, indium, niobium, platinum, silver, tantalum, tin and tungsten. |
The Discovery of Tetrahydrocannabinol
Anandamide Ananda - bliss delight mide - Methanolamide The endocannabinoid system is involved in all human diseases. In Osteo, CB1 and CB2 receptors either help degrade the bone or help rebuild the bone. THC blocks the development of cancer. |
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University of Guelph study shows 1 in 3 vitamins and supplements proved to be fakesIn 2012, University of Guelph botanist Steven Newmaster and his team randomly selected 44 herbal supplements sold in Canada and the U.S. Their study shows 60 percent of vitamin and supplement products contained ingredients not listed on their labels and 1 in 3 proved to be fakes.
https://www.cbc.ca/fifth/blog/university-of-guelph-study-shows-1-in-3-vitamins-and-supplements-proved-towww.cbc.ca/fifth/blog/university-of-guelph-study-shows-1-in-3-vitamins-and-supplements-proved-to |
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Uranium: Radiation
Canada is one of the world's largest uranium producers with 20.5% (9,000 tonnes) of global output in 2008. Highest levels of exposure occur in an occupational setting in mines where uranium and thorium are present. Naturally occurring radon can also accumulate in workplace and residential buildings, especially in basements. Uranium accumulates mainly in the bones (66%), kidneys (8%), and liver (16%) (ICRP, 1996), and it is eliminated with the urine, rapidly from the blood and slowly from organ depots (ICRP, 1996; La Touche et al., 1987). The chemical toxicity has been associated with hepatic, lung, and renal injury (UNSCEAR, 1988). If uranium has already entered the target organs, therapy with chelating agents is initiated. In clinical practice, these agents are usually used as antidotes in intoxications, both acute and chronic, with metals. These compounds bind to the metal and improve its excretion. Moreover, in some cases, they decrease the toxicity of the metal because they prevent it from binding to its target cells. |
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Note:
* Chronic ingestion of uranium in drinking water: a study of kidney bioeffects in humans * Bone is the primary site for prostate cancer metastases, with 90% of 1,589 autopsied mCRPC patients exhibiting metastatic bone disease. Saad, F., Fleshner, N., So, A., Le Lorier, J., Perrault, L., Poulin-Costello, M., Rogoza, R., & Robson, E. (2018). The burden of symptomatic skeletal events in castrate-resistant prostate cancer patients with bone metastases at three Canadian uro-oncology centres. Canadian Urological Association Journal, 12(12). https://doi.org/10.5489/cuaj.5053 – 2018 https://cuaj.ca/index.php/journal/article/view/5053 * Source: https://academic.oup.com/toxsci/article/118/2/324/1648537, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680588/, https://nuclearsafety.gc.ca/eng/resources/fact-sheets/radon-fact-sheet.cfm * Image: http://web.mit.edu/12.000/www/m2016/finalwebsite/solutions/deposits.html |
Radon: Radiation, Canada
Radon is a cancer-causing radioactive gas produced by the natural decay of uranium in rocks and soils. Most Canadians have never heard of radon, but it is the second-leading cause of lung cancer and the primary cause of lung cancer among non-smokers. Health Canada estimates that 16 per cent of lung cancer deaths in Canada are attributable to radon exposure. Canadians are exposed to radon when it escapes from the ground into the air. Concentrations in outdoor air are low, but radon can become trapped and accumulate in buildings, reaching high levels in indoor air In 1987, the International Agency for Research on Cancer (IARC) first stated that radon causes lung cancer in humans, based largely on studies of underground haematite miners with high exposures to radon (specifically radon-222 and its decay products). There is now evidence from studies of residential radon exposure within the general population that further supports a causal association between radon exposure and an increased risk of lung cancer. Source: https://www.cancercareontario.ca/en/statistical-reports/cancer-risk-factors-ontario-evidence-summary-0 https://www.epa.gov/radon/health-risk-radon https://davidsuzuki.org/wp-content/uploads/2017/09/revisiting-canada-radon-guideline.pdf Image: http://web.mit.edu/12.000/www/m2016/finalwebsite/solutions/deposits.html Source Right: https://www.cancercareontario.ca/sites/ccocancercare/files/assets/CCORiskFactorsOtherRadiation.pdf |
A pooled analysis of 11 cohort studies found a 1.2–3.2 times greater risk of lung cancer at 100 working-level months among radon-exposed underground miners; a consistent dose-response relationship with cumulative radon exposure was also apparent. Residential exposure to radon has been associated with a 10%–40% increase in lung cancer risk, from lower through higher exposures, with pooled analyses from North America, Europe, and China demonstrating a consistent dose-response relationship.
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Voici la belle table des symboles alchimiques d'Aristotle Pramagioulis site : www.egregoredesign.com
The Art of Alchemy