NIH: Gain of Function
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Genetic Diseases are merely 'Risk Markers'. We are conditioned to believe that our inherited genes create diseases but scientists have discovered that it is not our genes that create diseases but that it is our own biochemical, physical, and emotional reaction to our environment that 'switches on' certain genes in our body that creates diseases. Markers in a genetic makeup give one a tendency to develop RA and so it is believed that an environmental factor such as a virus, may trigger the development of RA in the 'B' blood type persons while bacteria may trigger the development of RA in the in 'A' blood type. The growing knowledge about the pathogenesis of SARS-CoV-2 infection is leading to the introduction of drugs commonly used for the treatment of rheumatoid arthritis (RA) even for the management of more complex cases of COVID-19. (1), (2) Read more on Genetics and Environment - Mercury - LeadMercury Poisoning
40:27 - Epigenetic Alterations
40:27 - Epigenetic Alterations
It's not a gene mutation, it's a gene activation. What we used to think. that our genes are a destiny, we now know that they're not our destiny, that only a small percent of our genes dictates what happens to us. Then our destiny is about what those genes are told to do and what those genes are told to do has so much to do with what we're exposed to.
So we know that smoking, even eating rice, can change your epigenetic profile; so any vaccination injection is sure to change the epigenetic profile.
What we find here, is that after and it happens by signaling, depending on what's hitting the outside of the cell, be it Aluminium or formaldehyde or tetanus toxoid, we will see different signals go into the cell and different instructions will be given to the genes which will make protein. We see epigenetic alterations resulting in up regulation of genes that are associated with genetic disorders cardiovascular disease, gastrointestinal disease, immunological disease, connective tissue disorders, developmental disorders that the list was very long and everyone responded differently to each other. There are things called cytokines which are chemicals in the blood that that tell your cells how to respond during an infection and they found that those cytokines were different in different in individuals.
It's not a gene mutation, it's a gene activation. What we used to think. that our genes are a destiny, we now know that they're not our destiny, that only a small percent of our genes dictates what happens to us. Then our destiny is about what those genes are told to do and what those genes are told to do has so much to do with what we're exposed to.
So we know that smoking, even eating rice, can change your epigenetic profile; so any vaccination injection is sure to change the epigenetic profile.
What we find here, is that after and it happens by signaling, depending on what's hitting the outside of the cell, be it Aluminium or formaldehyde or tetanus toxoid, we will see different signals go into the cell and different instructions will be given to the genes which will make protein. We see epigenetic alterations resulting in up regulation of genes that are associated with genetic disorders cardiovascular disease, gastrointestinal disease, immunological disease, connective tissue disorders, developmental disorders that the list was very long and everyone responded differently to each other. There are things called cytokines which are chemicals in the blood that that tell your cells how to respond during an infection and they found that those cytokines were different in different in individuals.
Source: Dr. Humphries on tetanus, immunity and epigenetics - YouTube www.youtube.com/watch?v=hIgomZ06FFQ
Since the beneficial effects of vaccines are a result of changes in the immune system, it would not be surprising if some of the adverse effects were also a classification of immunologic reactions that can cause disease. (Coombs and Gell 1968). Vaccinations and risk of systemic lupus erythematosus and rheumatoid arthritis: A systematic review and meta-analysis by (BinWang et al., 2012) conclude, "This study suggests that vaccinations are related to increased risks of SLE and RA. More and larger observational studies are needed to further verify the findings above and to assess the associations of vaccinations with other rheumatic diseases."
Genetic Alterations
Miracle in Japan www.youtube.com/watch?v=E1GF0H9V_1g More people in Asia particularly in Japan have a defense enzyme called APOBEC3A which is a defense enzyme that people have, that helps them to defend against viruses. |
See Some Examples
Resistant to Cancer
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Resistant to HIV
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Life Saving Gene Therapy
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Dr. Remi Buisson PhD (UCI) APOBEC3A expression in cancer & how it affects cancer development
www.youtube.com/watch?v=SNAVbKD6mx0 |
2018. Scientist claims he helped create world's first genetically-modified babies
www.youtube.com/watch?v=b0HvLaXOhEY&t=4s |
Helping Families Take Charge of Adenosine Deaminase (ADA)-Severe Combined Immunodeficiency (SCID)
www.youtube.com/watch?v=6EaKKIe3aas |
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Transgenic
A transgenic animal is where you take a piece of DNA that's not normally found in that animal and place it back among its normal chromosomes. So for example, you can make a transgenic by having a piece of DNA that you clone in a laboratory and inject it into a fertilized egg of a mouse embryo, for example, then that becomes integrated into the chromosome. And then when that mouse is born, it can transmit that extra piece of DNA to its offspring. Transgenic animals can be used to model human diseases. So for example, if there was a particular human disease that results from having a mutated protein overexpressed, you can make a transgenic animal that also makes that same mutated protein overexpressed. This then provides us with a mouse model that then mimics that human disease that we can go into and actually study how that overexpressed mutant protein causes the disease, and we can also use that animal to test therapeutic interventions.
William Pavan, Ph.D. Podcast: www.genome.gov/genetics-glossary/Transgenic
William Pavan, Ph.D. Podcast: www.genome.gov/genetics-glossary/Transgenic
Applications of animal transgenesis may be divided into three major categories: Animal transgenesis started in 1980.
(i) to obtain information on gene function and regulation as well as on human diseases,
(ii) to obtain high value products (recombinant pharmaceutical proteins and xeno-organs for humans) to be used for human therapy
(iii) to improve animal products for human consumption. https://pubmed.ncbi.nlm.nih.gov/16008757/
(i) to obtain information on gene function and regulation as well as on human diseases,
(ii) to obtain high value products (recombinant pharmaceutical proteins and xeno-organs for humans) to be used for human therapy
(iii) to improve animal products for human consumption. https://pubmed.ncbi.nlm.nih.gov/16008757/
- The advance in the generation of pigs to be used as the source of organs for patients and in the preparation of pharmaceutical proteins from milk and other possible biological fluids from transgenic animals is described.